老年性聋发病机制研究进展
Research Progress on the Etiopathogenesis of Presbycusis
王松 1韩贺舟 1马秀岚1
作者信息
- 1. 中国医科大学附属盛京医院耳鼻咽喉头颈外科(沈阳 110004)
- 折叠
摘要
老年性聋是以隐匿性、缓慢进行性双侧感音神经性听力下降为特征的疾病,其发生和发展是一个多因素作用的过程,每种因素的作用在个体间差异较大.针对老年性聋的发病机制,目前已有一定研究,主要可分为离子通道异常、耳蜗突触病变、活性氧自由基、激素作用、线粒体异常、遗传因素等诸多方面,本文对近年来老年性聋发病机制进行总结.
Abstract
Presbycusis is a disease characterized by hidden and slowly progressive bilateral sensorineural hear-ing loss.Its occurrence and development is a multifactorial process.The expression of each factor varies greatly a-mong individuals.Currently,there have been some studies on the pathogenesis of presbycusis,which can be catego-rized into ion channel abnormalities,cochlear synaptopathy,reactive oxygen species,hormone effects,mitochondrial abnormalities,genetic factors and vari other factors.This review summarizes the pathogenesis of presbycusis in re-cent years.
关键词
老年性聋/年龄相关性听力损失/发病机制Key words
Presbycusis/Age-related hearing loss/Etiopathogenesis引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据