摘要
前庭性偏头痛(vestibular migraine,VM)是临床常见的眩晕与偏头痛共存的前庭疾病,视觉诱发的眩晕是VM的典型前庭症状之一.VM相关视觉性眩晕的临床表现多样,受焦虑状态、晕动病、年龄等因素影响.解剖生理方面的联系、凝视不稳定、视觉前庭整合缺陷、感觉重塑受损、前庭中枢通路敏化、5-羟色胺和谷氨酸-谷氨酰胺循环等神经递质等多个机制可能导致了 VM相关视觉性眩晕的发生.
Abstract
Vestibular migraine(VM)is a common vestibular disorder in which vertigo and migraine coexist,and visually induced vertigo is one of the typical vestibular symptoms of VM.The clinical manifestations of VM re-lated visual vertigo are various,which are affected by anxiety,motion sickness,age and other factors.Multiple mechanisms such as anatomical and physiological connections,gaze instability,visual vestibular integration defects,impaired sensory remodeling,sensitization of the central vestibular pathway,5-hydroxytryptamine and glutamate-glutamine cycle and other neurotransmitters may lead to VM-related visual vertigo.
基金项目
河南省中医药科学研究专项(2018JDZX012)