Objective To study the influencing factors of postoperative recurrence of vocal cord leukoplakia and establish a clinical prediction model.Methods A total of 386 patients with vocal cord leukoplakia treated in our hospital from February 2016 to February 2020 were selected retrospectively.According to the follow-up results,the patients were divided into two groups:recurrent group(n=89)and non-recurrent group(n=297).The general and clinical data of the two groups were collected.The influencing factors of postoperative recurrence of vocal cord leu-koplakia were screened by univariate analysis and Logistic regression analysis,and the Logistic risk prediction model was established.The model was internally verified by R software and boostrap method.Results Age(OR=0.924),drinking history(OR=1.946),voice abuse(OR=2.436),laryngopharyngeal reflux(OR=0.487),mod-erate dysplasia(OR=0.420)and severe dysplasia(OR=0.303)were the influencing factors of postoperative recur-rence of vocal cord leukoplakia.The internal verification AUC of the model was 0.777,95％the confidence interval was 0.663～0.825,and the model fit well.Conclusion The postoperative recurrence of vocal cord leukoplakia is related to the patient's age,leukoplakia range,pathological morphology and laryngopharyngeal reflux.
Vocal cord leukoplakiaPostoperative recurrenceRisk factorsPredictive model
NETL
NSTL
万方数据
