Objective To investigate the clinical utility of dapagliflozin combined with bifidobacterium trifidum in the treatment of diabetic diarrhea.Methods A total of 80 patients with diabetic diarrhea admitted to Ninghua County Gen-eral Hospital from January 2021 to December 2022 were selected as the study objects,and were divided into control group and observation group according to random number table method,with 40 cases in each group.The control group was treated with metformin + dagaglizin + montmorillonite powder,and the observation group was treated with bifidobacterium triple viable bacteria on this basis.The therapeutic effect,blood glucose level and intestinal flora of the two groups were observed and compared.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no sta-tistically significant differences in fasting blood glucose,2-hour postprandial blood glucose and glycated hemoglobin between the two groups(all P>0.05).After treatment,the blood glucose level of the two groups was lower than before treatment,and the value of each index in the observation group was lower than that in the control group,and the differ-ences were statistically significant(all P<0.05).Before treatment,there was no statistically significant difference in the levels of bifidobacterium,enterobacter,lactobacillus and enterococcus between the two groups(all P>0.05).After treat-ment,the levels of bifidobacterium and lactobacillus in the two groups were higher than before treatment,and the lev-els of enterobacterium and enterococcus were lower than before treatment,and the levels of bifidobacterium and lacto-bacillus in the observation group were higher than those in the control group,while the levels of enterobacterium and enterococcus were lower than those in the control group,and the difference was statistically significant(all P<0.05).Conclusion When patients with diabetic diarrhea take dagaglipin and bifidobacterium triple live bacteria,the effect is significant,which can regulate the intestinal flora of patients and improve the blood sugar level of patients.
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