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激光联合复方血栓通胶囊治疗糖尿病视网膜病变合并黄斑水肿的疗效分析

Therapeutic Effect of Laser Combined with Compound Xueshuantong Capsule on Diabetic Retinopathy Complicated with Macular Edema

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目的 探析糖尿病视网膜病变合并黄斑水肿患者采用激光结合复方血栓通胶囊治疗的效果.方法 选取2022年1月—2023年1月联勤保障部队第九四〇医院眼科收治的100例糖尿病视网膜病变合并黄斑水肿患者为研究对象,依据随机数表法分为两组,各50例.对照组予以激光治疗,观察组在对照组的基础上予以复方血栓通胶囊治疗.比较两组凝血功能指标、黄斑厚度、视力水平及炎性指标水平.结果 观察组活化部分凝血活酶时间、凝血酶时间、凝血酶原时间均短于对照组,纤维蛋白原水平高于对照组,差异有统计学意义(P均<0.05);观察组黄斑厚度低于对照组、视力水平高于对照组,差异有统计学意义(P均<0.05);观察组炎性指标水平优于对照组,差异有统计学意义(P<0.05).结论 糖尿病视网膜病变合并黄斑水肿患者可选取多种方法治疗,激光与复方血栓通胶囊联合治疗可良好改善患者的黄斑厚度,调节其视力水平,降低患者机体炎症水平.
Objective To explore the effect of laser combined with compound Xueshuantong capsule on diabetic reti-nopathy complicated with macular edema.Methods A total of 100 patients with diabetic retinopathy combined with macular edema who were admitted to the Department of Ophthalmology of the 940th Hospital of the Joint Logistics Support Force from January 2022 to January 2023 were selected as the research objects.According to the random number table method,they were divided into two groups,with 50 cases in each group on the basis of the control group.The control group was treated with laser,and the observation group was treated with compound Xueshuantong capsule on the basis of the control group.The coagulation funtion indexes,macular thickness,visual acuity and inflammatory indexes were compared between the two groups.Results The activated partial thromboplastin time,thrombin time and prothrombin time in the observation group were shorter than those in the control group,and the fibrinogen level was higher than that in the control group,and the differences were statistically significant(all P<0.05).The macular thick-ness of the observation group was lower than that of the control group,and the visual acuity level was higher than that of the control group,and the differences were statistically significant(both P<0.05).The levels of inflammatory indica-tors in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Patients with diabetic retinopathy complicated with macular edema can be treated with a vari-ety of methods.Laser combined with compound Xueshuantong capsule can effectively improve the macular thickness of patients,adjust their visual acuity level,and reduce the level of body inflammation in patients.

Diabetic retinopathyMacular edemaLasersCompound Xueshuantong capsule

张文俊、曹芳、苏晓庆

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联勤保障部队第九四〇医院眼科,甘肃兰州 730050

糖尿病视网膜病变 黄斑水肿 激光 复方血栓通胶囊

甘肃省自然科学基金

23JRRA537

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(1)
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