糖尿病新世界2024,Vol.27Issue(1) :154-157.DOI:10.16658/j.cnki.1672-4062.2024.01.154

研究眼底激光联合康柏西普治疗糖尿病性视网膜病变的临床效果

Study on the Clinical Effect of Fundus Laser Combined with Conbercept in the Treatment of Diabetic Retinopathy

张晓燕
糖尿病新世界2024,Vol.27Issue(1) :154-157.DOI:10.16658/j.cnki.1672-4062.2024.01.154

研究眼底激光联合康柏西普治疗糖尿病性视网膜病变的临床效果

Study on the Clinical Effect of Fundus Laser Combined with Conbercept in the Treatment of Diabetic Retinopathy

张晓燕1
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作者信息

  • 1. 栖霞市人民医院眼科,山东烟台 265300
  • 折叠

摘要

目的 探究增殖期糖尿病性视网膜病变患者应用眼底激光联合康柏西普的治疗效果.方法 选取2021年3月—2023年3月栖霞市人民医院收治的150例增殖期糖尿病性视网膜病变患者,所有的患者根据电脑抽取法随机分成单一组(眼底激光术治疗)与联合组(眼底激光术联合康柏西普治疗),各75例.比较两组患者的治疗效果、手术指标、血液流变学指标、黄斑厚度、视力水平、炎症因子水平及不良事件发生情况.结果 联合组患者的治疗有效率、最佳矫正视力水平均高于单一组,术中与术后出血率、黄斑厚度、眼底黄斑水肿消失时间、视网膜新生血管消失时间均低于单一组,差异有统计学意义(P均<0.05).结论 通过采取眼底激光联合康柏西普进行治疗,能够有效地提高患者的治疗效果,改善血液流变学指标、黄斑厚度及炎症因子水平,降低不良事件发生概率.

Abstract

Objective To investigate the therapeutic effect of application of fundus laser combined with conbercept in patients with proliferative diabetic retinopathy.Methods 150 patients with proliferative diabetic retinopathy were ad-mitted to Qixia People's Hospital from March 2021 to March 2023,and all the patients were randomly divided into a single group(fundus laser)and a combined group(fundus laser combined with conbercept)of 75 cases each group ac-cording to the computerized sampling method.The treatment effect,surgical indexes,blood rheology indexes,macular thickness,visual acuity level,inflammatory factor level and the occurrence of adverse events were compared between the two groups.Results The treatment efficiency and best corrected visual acuity level of patients in the combined group were higher than those in the single group,and the intraoperative and postoperative hemorrhage rate,macular thickness,time for the disappearance of fundus macular edema,and time for the disappearance of retinal neovascular-ization were lower than those in the single group,and the differences were statistically significant(all P<0.05).Conclusion By adopting fundus laser combined with conbercept for treatment,it can effectively improve the therapeu-tic effect of the patients,improve the blood rheology index,macular thickness and inflammatory factor level,and re-duce the probability of adverse events.

关键词

增殖期糖尿病性视网膜病变/康柏西普/眼底激光/炎症因子

Key words

Proliferative diabetic retinopathy/Conbercept/Fundus laser/Inflammatory factor

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量12
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