糖尿病新世界2024,Vol.27Issue(1) :158-161.DOI:10.16658/j.cnki.1672-4062.2024.01.158

尿蛋白和尿微量白蛋白在糖尿病肾病检验中的临床应用

Clinical Application of Urine Protein and Urine Microalbumin in Diabetic Nephropathy Testing

陈媛 杨孟 詹秋月
糖尿病新世界2024,Vol.27Issue(1) :158-161.DOI:10.16658/j.cnki.1672-4062.2024.01.158

尿蛋白和尿微量白蛋白在糖尿病肾病检验中的临床应用

Clinical Application of Urine Protein and Urine Microalbumin in Diabetic Nephropathy Testing

陈媛 1杨孟 1詹秋月1
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作者信息

  • 1. 福建省三明市沙县区总医院检验科,福建三明 365000
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摘要

目的 研究在糖尿病肾病检验中对患者实施尿蛋白检测、尿微量白蛋白检测的临床价值.方法 选取2020年1月—2021年1月福建省三明市沙县区总医院检验科收治的50例糖尿病肾病患者作为本研究的观察组,另选同期常规检查的健康者50例作为对照组,对两组研究对象实施白蛋白检测和尿微量白蛋白检测,比较观察组单独检测与联合检测的结果,比较尿蛋白、尿微量白蛋白、联合检测糖尿病肾病的灵敏度、特异度、阳性预测值.结果 观察组24 h尿蛋白、尿微量白蛋白含量均高于对照组,差异有统计学意义(P均<0.05);联合检测灵敏度、阳性预测值均高于尿蛋白及尿微量白蛋白检测,差异有统计学意义(P均<0.05);特异度组间比较,差异无统计学意义(P>0.05).结论 尿蛋白检测、尿微量白蛋白检测均可应用于糖尿病肾病的临床诊断之中,二者联合运用,可为临床治疗提供重要参考.

Abstract

Objective To study the clinical value of implementing urine protein test and urine microalbumin test for patients in diabetic nephropathy test.Methods 50 patients with diabetic nephropathy in the Department of Laboratory of Sanming Shaxian District General Hospital of Fujian Province from January 2020 to January 2021 were admitted and selected as the observation group of this study,and another 50 healthy people who were routinely examined dur-ing the same period were selected as the control group.Albumin test and urine microalbumin test were performed on the two groups,and the results of the observation group were compared with those of the combined test,the sensitivity,specificity,and positive predictive value of urine protein,urine microalbumin,and the combined test for diabetic ne-phropathy were compared.Results The 24 h urine protein and urine microalbumin levels in the observation group were higher than those in the control group,and the differences were statistically significant(both P<0.05).The sensi-tivity and positive predictive value of the combined test were higher than those of the urine protein and urine microal-bumin test,and the differences were statistically significant(both P<0.05).There was no statistically significant differ-ence in specificity between two groups(P>0.05).Conclusion Urine protein test and urine microalbumin test can be applied in the clinical diagnosis of diabetic nephropathy,the joint application of the two can provide an important ref-erence for clinical treatment.

关键词

尿蛋白/尿微量白蛋白/糖尿病肾病检验/临床诊断

Key words

Urine protein/Urine microalbumin/Diabetic nephropathy test/Clinical diagnosis

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量11
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