糖尿病新世界2024,Vol.27Issue(1) :167-170.DOI:10.16658/j.cnki.1672-4062.2024.01.167

复方血栓通片联合参芪降糖颗粒治疗糖尿病肾病的效果分析

Analysis of the Effect of Compound Xueshuantong Tablets Combined with Shenqi Jiangtang Granules in the Treatment of Diabetic Nephropathy

张建文
糖尿病新世界2024,Vol.27Issue(1) :167-170.DOI:10.16658/j.cnki.1672-4062.2024.01.167

复方血栓通片联合参芪降糖颗粒治疗糖尿病肾病的效果分析

Analysis of the Effect of Compound Xueshuantong Tablets Combined with Shenqi Jiangtang Granules in the Treatment of Diabetic Nephropathy

张建文1
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作者信息

  • 1. 永安市中医院中药房,福建永安 366000
  • 折叠

摘要

目的 探讨复方血栓通片联合参芪降糖颗粒在糖尿病肾病临床治疗中的应用疗效.方法 选取2020年8月—2022年10月永安市中医院收治的86例糖尿病肾病患者作为研究对象,按照随机数表法,分为观察组(复方血栓通片联合参芪降糖颗粒+常规治疗)和对照组(常规治疗),每组43例,比较两组患者的治疗效果.结果 观察组的治疗有效率(93.02%)高于对照组(76.74%),差异有统计学意义(P<0.05).治疗后,观察组的空腹血糖值、餐后2 h血糖值、糖化血红蛋白水平均低于对照组,差异有统计学意义(P均<0.05);观察组的血肌酐、尿素氮水平低于对照组,差异有统计学意义(P均<0.05);观察组的超敏C反应蛋白水平、肿瘤坏死因子-α水平低于对照组,差异有统计学意义(P均<0.05);观察组的水肿、倦怠无力、腰膝酸软等中医症候积分低于对照组,差异有统计学意义(P均<0.05).结论 复方血栓通片与参芪降糖颗粒的联合应用,对于治疗糖尿病肾病具有良好的疗效.

Abstract

Objective To explore the efficacy of the application of compound Xueshuantong tablets combined with Shenqi Jiangtang granules in the clinical treatment of diabetic nephropathy.Methods A total of 86 diabetic nephropa-thy patients admitted to Yongan Hospital of Traditional Chinese Medicine from August 2020 to October 2022 were se-lected as the study objects.According to the random number table method,they were divided into observation group(Compound Xuesuantong Tablet combined with Shenqi Jiangtang Granules + conventional treatment)and control group(conventional treatment),with 43 cases in each group.The therapeutic effects of the two groups of patients were compared.Results The effective rate of observation group(93.02%)was higher than that of control group(76.74%),and the difference was statistically significant(P<0.05).After treatment,fasting blood glucose,2-hour postprandial blood glucose and the level of glycosylated hemoglobin in observation group were lower than those in control group,and the differences were statistically significant(all P<0.05).Serum creatinine and urea nitrogen levels in observation group were lower than those in control group,and the differences were statistically significant(both P<0.05).The lev-els of hypersensitive C-reactive protein and tumor necrosis factor-α in observation group were lower than those in control group,and the differences were statistically significant(both P<0.05).The scores of traditional Chinese medi-cine syndrome such as edema,fatigue and weakness,waist and knee weakness in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion The com-bined application of compound Xueshuantong tablets and Shenqi Jiangtang granules has good efficacy in the treatment of diabetic nephropathy.

关键词

复方血栓通片/参芪降糖颗粒/糖尿病肾病

Key words

Compound Xueshuantong tablet/Shenqi Jiangtang granules/Diabetic nephropathy

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量12
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