糖尿病新世界2024,Vol.27Issue(1) :190-194.DOI:10.16658/j.cnki.1672-4062.2024.01.190

肾康注射液用于糖尿病肾病治疗的快速卫生技术评估

Rapid Hygienic Technical Evaluation of Shenkang Injection for the Treat-ment of Diabetic Nephropathy

刘琳 刘娜 马超群 窦琬婷
糖尿病新世界2024,Vol.27Issue(1) :190-194.DOI:10.16658/j.cnki.1672-4062.2024.01.190

肾康注射液用于糖尿病肾病治疗的快速卫生技术评估

Rapid Hygienic Technical Evaluation of Shenkang Injection for the Treat-ment of Diabetic Nephropathy

刘琳 1刘娜 1马超群 1窦琬婷1
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作者信息

  • 1. 北京市密云区中医医院药剂科,北京 101500
  • 折叠

摘要

目的 快速卫生技术评估肾康注射液用于糖尿病肾病治疗的有效性、安全性及经济性,为临床实践和决策者提供循证依据.方法 检索PubMed、Cochrane Library、Embase和CNKI、VIP、WanFang、SinoMed等数据库以及卫生技术评估(Health Technology Assessment,HTA)网站,设置检索文献发表时间为2000年1月1日—2023年5月31日,对肾康注射液用于糖尿病肾病治疗的相关循证证据进行汇总分析.结果 共纳入8篇文献,结果显示,与常规治疗相比,肾康注射液在尿素氮(Blood Urea Nitrogen,BUN)、血肌酐(Serum Creatinine,SCr)、尿白蛋白排泄率(Urinary Albumin Excretion Rates,UAER)和总有效率等方面均有明显改善,差异有统计学意义(P均<0.05).肾康注射液总体安全性较好,其不良反应以注射部位疼痛、潮红为主,但经济性方面不占优势.结论 肾康注射液用于糖尿病肾病的治疗有较好的有效性、安全性,但其经济性不占优势.

Abstract

Objective Rapid health technology to evaluate the efficacy,safety and economy of Shenkang injection in the treatment of diabetic nephropathy,to provide evidence-based evidence for clinical practice and decision makers.Methods Searches were conducted on PubMed,Cochrane Library,Embase and CNKI,VIP,WanFang,SinoMed and health technology assessment(HTA)websites,and the publication time of the search literature was set from January 1,2000 to May 31,2023.The relevant evidence-based evidence of Shenkang injection in the treatment of diabetes ne-phropathy were summarized and analyzed.Results A total of 8 articles were included,and the results showed that compared with conventional treatment,Shenkang Injection showed significant improvements in blood urea nitrogen(BUN),serum creatinine(SCr),urinary albumin excretion rates(UAER)and total effective rate,and the differences were statistically significant(all P<0.05).The overall safety of Shenkang Injection is good,and its adverse reactions are mainly pain and redness at the injection site,but it does not have an advantage in terms of economy.Conclusion Shenkang injection has good efficacy and safety in the treatment of diabetic nephropathy,but its economy is not domi-nant.

关键词

肾康注射液/糖尿病肾病/循证评价

Key words

Shenkang injection/Diabetic nephropathy/Evidence-based evaluation

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
参考文献量15
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