首页|大柴胡汤加减结合常规西药治疗2型糖尿病的疗效及对临床症状积分、胰岛β细胞功能指标的影响

大柴胡汤加减结合常规西药治疗2型糖尿病的疗效及对临床症状积分、胰岛β细胞功能指标的影响

The Efficacy of Modified Dachaihu Decoction Combined with Conven-tional Western Medicine in the Treatment of Type 2 Diabetes and Its Im-pact on Clinical Symptom Scores and Pancreatic Beta Cell Function Indi-cators

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目的 探讨大柴胡汤加减结合常规西药治疗2型糖尿病的疗效及对临床症状积分、胰岛β细胞功能指标的影响.方法 选择2022年9月—2023年9月辽阳市中心医院收治的98例2型糖尿病患者为研究对象,以随机数表法分为两组,各49例.对照组用常规西药治疗,观察组用大柴胡汤加减结合常规西药治疗,比较两组的疗效及临床症状积分、胰岛β细胞功能指标.结果 观察组有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗12周的临床症状积分低于对照组,差异有统计学意义(P均<0.05);观察组治疗4周、治疗12周胰岛β细胞功能指数高于对照组,差异有统计学意义(P均<0.05).不良反应发生率组间比较,差异无统计学意义(χ2=0.178,P=0.674).结论 大柴胡汤加减结合常规西药治疗2型糖尿病的疗效较高,可降低临床症状积分,改善胰岛β细胞功能指标,且具有较高的安全性.
Objective To explore the efficacy of modified Dachaihu decoction combined with conventional western medicine in the treatment of type 2 diabetes and its impact on clinical symptom scores and pancreatic β-cell function indicators.Methods 98 patients with type 2 diabetes who were admitted to Liaoyang Central Hospital from September 2022 to September 2023 were selected as the research objects.The patients were divided into two groups by the ran-dom number table method,49 cases in wach group.The control group was treated with conventional Western medi-cine,and the observation group was treated with Dachaihu decoction combined with conventional Western medicine.The efficacy,clinical symptom scores,and pancreatic β-cell function indicators of the two groups were compared.Results The observation group had a higher effective rate than the control group,and the difference was statistically significant(P<0.05).The clinical symptom scores of the observation group after 12 weeks of treatment were lower than those of the control group,the differences were statistically significant(all P<0.05).The islet β-cell function index of the observation group after 4 weeks and 12 weeks of treatment were higher than those of the control group,the differ-ences were statistically significant(both P<0.05).There was no statistically significant difference in the occurrence of adverse reactions between groups,the difference was statistically significant(χ2=0.178,P=0.674).Conclusion Modi-fied Dachaihu decoction combined with conventional western medicine has high efficacy in treating type 2 diabetes.It can reduce clinical symptom scores,improve pancreatic β-cell function indicators,and has high safety.

Type 2 diabetesDachaihu decoctionSymptom scorePancreatic beta cell function

王丹青、王文昶

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辽阳市中心医院中医科,辽宁辽阳 111000

2型糖尿病 大柴胡汤 症状积分 胰岛β细胞功能

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(2)
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