Objective To investigate the effect of liraglutide therapy in elderly patients with type 2 diabetes.Methods A total of 52 elderly patients with type 2 diabetes admitted to Longyan First Hospital Affiliated to Fujian Medical Uni-versity from January 2021 to December 2022 were selected as the research objects and divided into two groups accord-ing to treatment methods,with 26 cases in each group.The control group was treated with metformin and the observa-tion group was treated with liraglutide.The fluctuations of blood glucose,blood lipids and changes in vascular endothe-lial function of the two groups were compared.Results After treatment,the levels of blood glucose,blood lipids and endothelin-1 were decreased in both groups,and the decrease was greater in the observation group compared with the control group,and the differences were statistically significant(all P<0.05).The levels of serum nitric oxide and blood-flow-mediated endothelial vasodilation function indexes were increased in both groups,and the increases were greater in the observation group than the control group,the differences were statistically significant(both P<0.05).Conclusion Liraglutide therapy in elderly patients with type 2 diabetes can improve blood glucose,blood lipids and vascular endothelial function,and has a good effect.
Type 2 diabetesLiraglutideBlood glucoseBlood lipidVascular endothelial function
维普
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