Objective To investigate the sensitivity and effect of serum C-peptide and glycosylated hemoglobin com-bined test in clinical diagnosis of diabetes mellitus.Methods 52 patients with suspected diabetes admitted to Shou-guang People's Hospital from May 2021 to July 2023 were selected as the study objects.Serum C-peptide and glyco-sylated hemoglobin were measured in all patients,and the single and combined diagnostic value of serum C-peptide and glycosylated hemoglobin was analyzed with the final clinical diagnosis result as the gold standard.Results The di-agnostic accuracy(82.69%),sensitivity(83.78%),specificity(80.00%),positive predictive value(91.17%)and nega-tive predictive value(66.67%)of serum C peptide combined with glycated hemoglobin test were higher than those of single serum C peptide and glycated hemoglobin test in diabetic patients,the differences were statistically significant(χ2=5.396,7.361,6.093,8.562,6.141,all P<0.05).Conclusion Serum C-peptide and glycosylated hemoglobin have a high detection rate in diabetic patients,and their combined examination can improve the diagnostic sensitivity,speci-ficity and accuracy,and can be used to guide clinical diagnosis and treatment.
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