首页|糖化血红蛋白和尿微量白蛋白对糖尿病肾病患者的检验价值研究

糖化血红蛋白和尿微量白蛋白对糖尿病肾病患者的检验价值研究

Study on the Testing Value of Glycosylated Hemoglobin and Urinary Mi-croalbumin in Patients with Diabetic Nephropathy

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目的 分析针对糖尿病肾病患者采取糖化血红蛋白(Glycosylated Hemoglobin,HbA1c)和尿微量白蛋白(Microalbuminuria,mALB)检验的作用.方法 选取2022年1-12月荣成市石岛人民医院检验科收治的150例糖尿病肾病患者作为研究对象,将其设为研究组,在同一时期选取150例到本院进行健康体检者,将其设为常规组,所有研究对象均接受HbA1c和mALB检验,分析HbA1c和mALB联合检验与单独检验的诊断结果及诊断效能.结果 研究组HbA1c与mALB水平均显著高于常规组,差异有统计学意义(P均<0.05);联合诊断的阳性率高于任意单一诊断的阳性率,差异有统计学意义(P均<0.05);联合诊断各项诊断效能均优于任意一项单一检查,差异有统计学意义(P均<0.05).结论 在糖尿病肾病诊断中运用HbA1c和mALB联合检验,其诊断阳性率较高,具有较高的诊断效能.
Objective To analyze the role of glycated hemoglobin(HbA1c)and urine microalbumin(mALB)testing in patients with diabetic nephropathy.Methods A total of 150 patients with diabetic nephropathy admitted to the Clini-cal Laboratory of Shidao People's Hospital of Rongcheng City from January to December 2022 were selected as the study group.During the same period,150 healthy examinees who went to the hospital for physical examination were selected as the routine group.All subjects were tested by HbA1c and mALB.The diagnostic results and efficacy of HbA1c and mALB combined test and single test were analyzed.Results The levels of HbA1c and mALB in the study group were significantly higher than those in the conventional group,the differences were statistically significant(both P<0.05).The positive rate of combined diagnosis was higher than that of any single diagnosis,and the differences were statistically significant(all P<0.05).The diagnostic efficacy of combined diagnosis was better than that of any single examination,and the differences were statistically significant(all P<0.05).Conclusion The combined test of HbA1c and mALB in the diagnosis of diabetic nephropathy has a higher positive rate and a higher diagnostic efficacy.

Diabetic nephropathyGlycosylated hemoglobinUrinary microalbuminDiagnosisEfficacy

张慧、邢海霞、张海燕

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荣成市石岛人民医院检验科,山东威海 264309

糖尿病肾病 糖化血红蛋白 尿微量白蛋白 诊断 效能

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(2)
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