首页|FPG、HbA1c水平变化与老年2型糖尿病视网膜病变患者视力严重程度的关系

FPG、HbA1c水平变化与老年2型糖尿病视网膜病变患者视力严重程度的关系

Relationship between Changes in FPG and HbA1c Levels and Vision Sever-ity in Elderly Patients with Type 2 Diabetic Retinopathy

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目的 探究空腹血糖(Fasting Blood Glucose,FPG)、糖化血红蛋白(Glycosylated Hemoglobin A1c,HbA1c)水平变化与老年2型糖尿病视网膜病变患者视力严重程度的关系.方法 选取2020年6月—2022年6月泉州市泉港区医院收治的92例2型糖尿病患者为研究对象,根据有无视网膜病变分为非视网膜病变组48例、视网膜病变组44例;根据视力损伤严重程度将视网膜病变患者分为轻度组15例、中度组14例、重度组15例.所有患者入院次日检测空腹血糖和视力情况,分析不同组间FPG、HbA1c水平;Pearson相关性分析FPG、HbA1c水平变化与患者视力严重程度关系.结果 视网膜病变组FPG和HbA1c水平均明显高于非视网膜病变组,差异有统计学意义(P均<0.05).中重度组FPG和HbA1c水平均明显高于轻度组,且重度组高于中度组,差异有统计学意义(P均<0.05).FPG、HbA1c与糖尿病视网膜病变患者视力损伤程度呈正相关(r=0.436、0.531,P均<0.001).结论 老年2型糖尿病视网膜病变患者FPG与HbA1c水平与视力损伤程度呈正相关.
Objective To explore the relationship between changes in fasting blood glucose(FPG)and glycated hemo-globin(HbA1c)levels and the severity of vision in elderly patients with type 2 diabetic retinopathy.Methods 92 pa-tients with type 2 diabetes admitted to Quangang District Hospital in Quanzhou City from June 2020 to June 2022 were selected as the research subjects.According to the presence or absence of retinopathy,they were divided into a non-retinopathy group of 48 cases and a retinopathy group of 44 cases.According to the severity of visual impairment,the patients with retinopathy were divided into a mild group of 15 cases,a moderate group of 14 cases,and a severe group of 15 cases.All patients were tested for fasting blood glucose and visual acuity on the day after admission,and FPG and HbA1c levels among different groups were observed.Pearson correlation analyzed the relationship between changes in FPG and HbA1c levels and the severity of the patient's vision.Results The levels of FPG and HbA1c in the retinopathy group were significantly higher than those in the non-retinopathy group,and the differences were sta-tistically significant(both P<0.05).The FPG and HbA1c levels in the moderate to severe group were significantly higher than those in the mild group,and the severe group was higher than the moderate group,and the differences were statistically significant(both P<0.05).FPG,HbA1c were positively correlated with the degree of visual impair-ment in patients with diabetic retinopathy(r=0.436,0.531,both P<0.001).Conclusion FPG and HbA1c levels are positively correlated with the degree of visual impairment in elderly patients with type 2 diabetic retinopathy.

Fasting blood glucoseGlycosylated hemoglobin A1cElderly type 2 diabetesDiabetic retinopathy

郑文彬、徐碧琳、林艳丰、姚贻华

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泉州市泉港区医院眼科,福建泉州 362800

福建医科大学附属第一医院中医科,福建福州 350000

福建医科大学附属第一医院眼科,福建福州 350000

空腹血糖 糖化血红蛋白 老年2型糖尿病 糖尿病视网膜病变

福建省自然科学基金青年创新项目

2020J05251

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(2)
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