首页|德谷胰岛素利拉鲁肽注射液联合二甲双胍在2型糖尿病患者治疗中的效果探讨

德谷胰岛素利拉鲁肽注射液联合二甲双胍在2型糖尿病患者治疗中的效果探讨

Efficacy of Tegu Insulin Liraglutide Injection Combined with Metformin in the Treatment of Type 2 Diabetes Mellitus

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目的 探究2型糖尿病患者采取德谷胰岛素利拉鲁肽注射液联合二甲双胍治疗的有效性.方法 回顾性选取太仓市第一人民医院于2021年9月—2023年10月收治的64例2型糖尿病患者的临床资料,根据治疗方案的不同,将其分成研究组和参考组,每组32例.所有患者均应用了二甲双胍,参考组加用达格列净,研究组加用德谷胰岛素利拉鲁肽注射液.比较两组的治疗效果、血糖水平、胰岛功能、临床指标.结果 研究组的治疗总有效率为96.88%,高于参考组的78.13%,差异有统计学意义(χ2=4.939,P<0.05).治疗后,研究组血糖水平优于参考组,差异有统计学意义(P<0.05).研究组的胰岛功能优于参照组,差异有统计学意义(P<0.05).研究组的体质量和总胆固醇水平均低于参考组,差异有统计学意义(P均<0.05).结论 在2型糖尿病患者治疗中选取德谷胰岛素利拉鲁肽注射液联合二甲双胍治疗,可以提高治疗效果,降低血糖水平,增强胰岛功能,优化临床指标.
Objective To investigate the effectiveness of Liraglutide injection combined with metformin in the treat-ment of patients with type 2 diabetes.Methods The clinical data of 64 patients with type 2 diabetes admitted to the First People's Hospital of Taicang City from September 2021 to October 2023 were retrospectively selected.According to different treatment plans,they were divided into study group and reference group,with 32 cases in each group.All patients were treated with metformin,the reference group with dagliprazin,the study group with Delgu insulin Liraglu-tide injection.The therapeutic effect,blood glucose level,islet function and clinical indexes of the two groups were compared.Results The total effective rate of the study group was 96.88%,higher than that of the reference group(78.13%),and the difference was statistically significant(χ2=4.939,P<0.05).After treatment,the blood glucose level of the study group was better than that of the reference group,and the difference was statistically significant(P<0.05).The islet function of the study group was better than that of the reference group,and the difference was statistically sig-nificant(P<0.05).The body mass and total cholesterol levels of the study group were lower than those of the reference group,and the differences were statistically significant(both P<0.05).Conclusion In the treatment of patients with type 2 diabetes,the combination of tegu insulin liraglutide injection and metformin can improve the therapeutic effect,reduce the blood glucose level,enhance the islet function and optimize the clinical indicators.

Tegu insulin liraglutide injectionType 2 diabetesMetformin

俞立波、李莉、杨熹

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太仓市第一人民医院内分泌科,江苏太仓 215400

德谷胰岛素利拉鲁肽注射液 2型糖尿病 二甲双胍

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(3)
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