血清C肽与糖化血红蛋白联合检验对糖尿病诊断的价值
Value of Serum C-peptide and Glycosylated Hemoglobin Combined Test in the Diagnosis of Diabetes Mellitus
程贝 1张鹏 1杨婷婷 1吴岢 1鞠健胜1
作者信息
- 1. 泰兴市中医院检验科,江苏泰兴 225400
- 折叠
摘要
目的 分析糖尿病诊断中血清C肽联合糖化血红蛋白检验的价值.方法 选取2022年1月—2023年6月泰兴市中医院收治的86例糖尿病患者为观察组,另选取同期86例健康体检者为对照组,均接受血清C肽、糖化血红蛋白检验,对比检验结果及诊断效能.结果 观察组血清C肽检测水平(0.83±0.23)μg/L较对照组的(1.49±0.44)μg/L低,糖化血红蛋白检测水平(9.27±1.15)%较对照组的(5.74±0.62)%高,差异有统计学意义(t =12.328、25.056,P均<0.05).联合检验灵敏度、特异度、准确度分别97.67%、96.51%、97.09%,均高于单一检测,差异有统计学意义(P均<0.05).结论 糖尿病患者的血清C肽、糖化血红蛋白水平与健康人差异明显,且联合检验的诊断效能较高.
Abstract
Objective To analyze the value of serum C-peptide combined with glycosylated hemoglobin test in the di-agnosis of diabetes.Methods A total of 86 patients with diabetes admitted to Taixing Hospital of Traditional Chinese Medicine from January 2022 to June 2023 were selected as the observation group,and 86 healthy people who under-went physical examination during the same period were selected as the control group.Serum C-peptide and glycated hemoglobin were tested to compare the test results and diagnostic efficacy.Results The detection level of serum C-peptide in the observation group(0.83±0.23)μg/L was lower than(1.49±0.44)μg/L in the control group,and the de-tection level of glycosylated hemoglobin(9.27±1.15)%was higher than(5.74±0.62)%in the control group,and the differences were statistically significant(t=12.328,25.056,both P<0.05).The sensitivity,specificity and accuracy of the combined test were 97.67%,96.51%and 97.09%,respectively,which were higher than that of the single test,and the differences were statistically significant(all P<0.05).Conclusion The levels of serum C-peptide and glycosylated hemoglobin in diabetic patients were significantly different from those in healthy people,and the diagnostic efficacy of combined test was higher.
关键词
血清C肽/糖化血红蛋白/联合检验/糖尿病/诊断Key words
Serum C-peptide/Glycosylated hemoglobin/Combined test/Diabetes mellitus/Diagnosis引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据