Objective To investigate the effect of insulin glargine combined with glimepiride on adverse reactions in patients with type 2 diabetes.Methods A total of 120 patients with type 2 diabetes admitted to Ninghua County Gen-eral Hospital,Sanming City,Fujian Province from December 2020 to August 2023 were selected as the study objects.They were divided into control group and study group by random number table method,with 60 cases in each group.The control group received insulin glargine and the study group was treated with glimepiide based on the control group.Results After treatment,the total effective rate of the study group was higher than that of the control group,and the incidence of adverse reactions was lower than that of the control group,and the differences were statistically sig-nificant(both P<0.05).After treatment,glycated haemoglobin A1c,2 hours postprandial blood glucose and fasting blood glucose in the study group were lower than those in the control group,and homeostasis model assessment-β and homeostasis model assessment-insulin resistance were higher than those in the control group,the differences were sta-tistically significant(all P<0.05).Conclusion The application effect of insulin glargine combined with glimepiride is good,it can reduce the blood glucose index and with less adverse reaction.
NETL
NSTL
维普
万方数据
