首页|微量注射泵胰岛素输注在糖尿病酮症酸中毒重症抢救中的效果

微量注射泵胰岛素输注在糖尿病酮症酸中毒重症抢救中的效果

Effect of Micro-injection Pump Insulin Infusion in the Treatment of Se-vere Diabetic Ketoacidosis

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目的 观察并评估在重度糖尿病酮症酸中毒患者中应用微静脉注射胰岛素的效果.方法 选取2020年8月—2023年8月山东省昌乐县人民医院重症医学科收治的64例糖尿病酮症酸中毒重症患者为研究对象,按随机数表法分为对照组和观察组,每组32例.抢救治疗时两组分别采用持续静脉滴注胰岛素、微量注射泵输注胰岛素治疗,对比两组血糖、相关临床指标.结果 两组治疗前随机血糖、血糖水平恢复至正常值时间对比,差异无统计学意义(P均>0.05);观察组治疗后2、4、6 h随机血糖水平高于对照组,治疗后8 h随机血糖低于对照组,差异有统计学意义(P均<0.05);观察组纠正糖尿病酮症酸中毒胰岛素用量、低血糖反应发生人次少于对照组,血酮体转阴时间、平均住院时间短于对照组,差异有统计学意义(P均<0.05).结论 微量注射泵胰岛素输注的治疗方式应用于抢救糖尿病酮症酸中毒重症患者效果显著,有利于促进血糖平稳下降,减少低血糖反应和胰岛素用量,具有较高的临床价值.
Objective To observe and evaluate the effect of intravenous insulin in patients with severe diabetic keto-acidosis.Methods 64 patients with severe diabetic ketoacidosis admitted to Department of Critical Care Medicine of Changle County People's Hospital,Shandong Province from August 2020 to August 2023 were selected as the study objects and were divided into the control group by random number table method and the observation group with 32 cases in each group.During rescue treatment,insulin was injected by continuous intravenous drip and micro-injection pump respectively in the two groups.The blood glucose,related clinical indicators and satisfaction with treatment ef-fect were compared between the two groups.Results There was no statistically significant difference in random blood glucose before treatment and the time for blood glucose level to return to normal(both P>0.05).The random blood glu-cose levels of the observation group at 2,4,6 h after treatment were higher than those of the control group,and the random blood glucose level at 8 h after treatment was lower than that of the control group,the differences were statisti-cally significant(all P<0.05).The amount of insulin used to correct diabetic ketoacidosis(DKA)and number of pa-tients with hypoglycemia reaction was less than those of the control group,the time of blood ketone body turning nega-tive and the average length of hospital stay were shorter than those of the control group,the differences were statisti-cally significant(all P<0.05).Conclusion The application of micro-injection pump insulin infusion in the treatment of severe diabetic ketoacidosis has a high effect,which is conducive to promoting the steady decline of blood sugar,re-ducing hypoglycemia reaction and insulin dosage,and has high clinical value.

Diabetic ketoacidosisInsulinMicro-injection pumpRescueSevere case

陈加峰、刘子国、陈仁霞

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山东省昌乐县人民医院重症医学科,山东潍坊 262400

糖尿病酮症酸中毒 胰岛素 微量注射泵 抢救 重症

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(3)
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