Effect of Panretinal Laser Photocoagulation Combined with Anti Vascular Endothelial Growth Factor Drugs in the Treatment of Diabetes Related Neovascular Glaucoma
Objective To study the clinical effect of panretinal laser photocoagulation combined with anti vascular en-dothelial growth factor(VEGF)drugs in the treatment of diabetes related neovascular glaucoma.Methods A total of 70 patients with diabetic neovascular glaucoma admitted to the Nanping First Hospital,Affiliated to Fujian Medical University from September 2018 to September 2022 were selected as the study objects,and were divided into control group and observation group by random number table method,with 35 cases in each group.The control group was treated with whole-retina laser photocoagulation.The observation group was treated with VEGF drugs.The intraocular pressure level,peripapillary retinal never fiber layer(PNFL)thickness,visual acuity level,loss time of neovasculariza-tion and total incidence of complications were compared between the two groups.Results Before operation,there were no statistically significant difference in intraocular pressure,PNFL thickness and visual acuity between two groups(all P>0.05).After surgery,the visual acuity level of the observation group was higher than that of the control group,the in-traocular pressure level was lower than that of the control group,the PNFL thickness was greater than that of the con-trol group,the neovascularization time was shorter than that of the control group,and the total complication rate was lower,the difference were statistically significant(all P<0.05).Conclusion In the treatment of diabetes-related neovas-cular glaucoma,the application of VEGF drugs can achieve significant therapeutic effect in the process of full retinal laser photocoagulation.This treatment helps to improve the patient's symptoms,improve vision,and reduce the risk of recurrence.Therefore,for diabetes-related neovascular glaucoma patients,the combined application of VEGF drugs on the basis of total retinal laser photocoagulation treatment is an effective treatment.
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