首页|达格列净联合百令胶囊对糖尿病肾病的疗效及对肾功能、糖代谢的影响

达格列净联合百令胶囊对糖尿病肾病的疗效及对肾功能、糖代谢的影响

Efficacy of Dapagliflozin Combined with Bailing Capsules on Diabetic Ne-phropathy and Effects on Renal Function and Glucose Metabolism

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目的 分析在糖尿病肾病治疗中应用达格列净联合百令胶囊的效果和对患者肾功能及糖代谢指标的影响.方法 选取济宁医学院附属金乡县人民医院于2021年8月—2023年7月收治的102例糖尿病肾病患者作为研究对象,采取抽签法分成研究组和参比组,每组51例.参比组采取达格列净,研究组加用百令胶囊,对比两组临床疗效、肾功能指标、糖代谢水平.结果 研究组的有效率为96.08%,高于参比组的82.35%,差异有统计学意义(χ2=4.993,P=0.025);治疗后,研究组的肾功能指标优于参比组,差异有统计学意义(P<0.05);研究组糖代谢水平优于参比组,差异有统计学意义(P<0.05).结论 在糖尿病肾病治疗中采用达格列净联合百令胶囊,可以提高临床疗效,促进肾功能恢复,还能够改善糖代谢水平.
Objective To analyze the effect of the application of dapagliflozin combined with Bailing capsule in the treatment of diabetic nephropathy and its influence on patients'renal function and glucose metabolism indexes.Methods A total of 102 diabetic nephropathy patients admitted to Jinxiang people's Hospital Affiliated to Jining Medi-cal College from August 2021 to July 2023 were selected as the study objects and divided into study group and refer-ence group by drawing lots,with 51 cases in each group.The reference group took daglipzin and the study group added bailing capsule.The clinical efficacy,renal function index and glucose metabolism level were compared be-tween the two groups.Results The effective rate of the study group was 96.08%,higher than that of the reference group(82.35%),and the difference was statistically significant(χ2=4.993,P=0.025).After treatment,the renal func-tion indexes of the study group were better than those of the reference group,and the difference was statistically sig-nificant(P<0.05).The glucose metabolism level of the study group was better than that of the reference group,and the difference was statistically significant(P<0.05).Conclusion The use of dapagliflozin combined with Bailing capsule in the treatment of diabetic nephropathy can improve the clinical efficacy,promote the recovery of renal function,and also improve the level of glucose metabolism.

Diabetic nephropathyBailing capsuleDapagliflozin

孟艳平、李凤艳、王府

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济宁医学院附属金乡县人民医院内分泌科,山东济宁 272200

糖尿病肾病 百令胶囊 达格列净

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(4)
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