Effect of Vaginal Lactobacillus Live Capsule Combined with Insulin Glargine in Clinical Treatment of Patients with Type 2 Diabetes Mellitus Complicated with Vaginitis
Objective To analyze the effect of vaginal Lactobacillus live capsule combined with insulin glargine in the clinical treatment of type 2 diabetes patients with vaginitis.Methods Sixty patients with type 2 diabetes mellitus com-bined with vaginitis admitted to Fujian Hospital of Shanghai Sixth People's Hospital from January 2022 to September 2023 were selected as the study objects and grouped into a control group and a study group of 30 cases each using the balanced sequential method.The control group was given Lactobacillus live capsule + metformin regimen,and the study group was given Lactobacillus live capsule + metformin + insulin glargine regimen.Two groups of patients were treated for 1 month,the blood glucose detection,blood glucose variability,and vaginal secretion detection were com-pared.Results Comparison of blood glucose detection situation between the two groups before treatment,and the dif-ference was not statistically significant(P>0.05);after treatment,compared with the control group,the study group has lower blood glucose level,and the difference was statistically significant(P<0.05).Comparison of blood glucose vari-ability between the two groups before treatment,and the difference was not statistically significant(P>0.05);after treat-ment,compared with the control group,the study group had lower blood glucose variability,and the difference was sta-tistically significant(P<0.05).Comparison of vaginal secretion detection between the two groups before treatment,and the difference was not statistically significant(P>0.05);after treatment,the level of improvement in vaginal pH was better in the study group compared to the control group,and the difference was statistically significant difference(P<0.05).Lactobacillus detection rate was higher in the study group than that in the control group,and the difference was statistically significant difference(χ2=6.666,P=0.009).Conclusion In the clinical treatment of patients with type 2 diabetes complicated with vaginitis,the application of vaginal Lactobacillus live capsule combined with insulin glargine can achieve a stable,obvious and long-term hypoglycemic effect,and can promote the change of vaginal envi-ronment and accelerate the remission of disease.
Type 2 diabetesVaginitisVaginal lactobacillus live capsuleInsulin glargine
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