首页|孕早期空腹血糖、餐后2h血糖及糖化血红蛋白联合检测在妊娠期糖尿病中的诊断价值

孕早期空腹血糖、餐后2h血糖及糖化血红蛋白联合检测在妊娠期糖尿病中的诊断价值

Diagnostic Value of Combined Detection of FPG,2 hPG and HbA1c in Gestational Diabetes during Early Pregnancy

扫码查看
目的 探讨孕早期空腹血糖(Fasting Plasma Glucose,FPG)、餐后 2 h血糖(2-hour Postprandial Plasma Glucose,2 hPG)及糖化血红蛋白(Glycosylated Hemoglobin A1c,HbA1c)联合检测对妊娠期糖尿病(Gestational Diabetes Mellitus,GDM)的诊断价值.方法 回顾性选取2022年1月—2023年6月三明市第二医院确诊为GDM的75例孕妇的临床资料(GDM组),选取同时期在本院产检健康的75例孕妇的临床资料,比较两组孕妇孕早期的FPG、2 hPG及HbA1c检测结果,分析FPG、2 hPG及HbA1c联合检测的诊断效能.结果 GDM组孕早期FPG、2 hPG及HbA1c指标水平均高于对照组,差异有统计学意义(P均<0.05);FPG、2 hPG及HbA1c联合检测的灵敏度(94.67%)、特异度(93.33%)、准确度(94.67%)均高于单一指标检测,差异有统计学意义(P均<0.05).结论 孕早期FPG、2 hPG及HbA1c指标对GDM有较好的联合诊断价值.
Objective To explore the diagnostic value of combined detection of fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 hPG)and glycosylated hemoglobin A1c(HbA1c)in early pregnancy for gestational dia-betes mellitus(GDM).Methods The clinical data of 75 pregnant women diagnosed with GDM in Sanming Second Hos-pital from January 2022 to June 2023 were retrospectively selected(GDM group).The clinical data of 75 healthy preg-nant women who underwent prenatal examinations in the hospital as the same period were selected(the control group).The results of FPG,2 hPG,and HbA1c detection in early pregnancy between two groups of research subjects were compared,and the diagnostic efficacy of FPG,2 hPG,and HbA1c combined detection were analyzed.Results The early pregnancy levels of FPG,2 hPG,and HbA1c indicators in the GDM group were higher than those in the control group,and the differences were statistically significant(all P<0.05).The sensitivity(94.67%),specificity(93.33%),and accuracy(94.67%)of the combined detection of FPG,2 hPG,and HbA1c combined detection were higher than those of single indicator detection,and the differences were statistically significant(all P<0.05).Conclusion Early pregnancy FPG,2 hPG,and HbA1c indicators have good combined diagnostic value for GDM.

Gestational diabetesGlycosylated hemoglobinFasting plasma glucose2-hour postprandial plasma glu-cose

陈淑萍、丁锦根、郑珠莲

展开 >

三明市第二医院检验科,福建永安 366000

妊娠期糖尿病 糖化血红蛋白:空腹血糖 餐后2h血糖

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(4)
  • 14