Effects of Olanzapine,Amisulapride Combined with Sitagliptin and Met-formin in the Treatment of Elderly Patients with Schizophrenia and Diabe-tes Mellitus and Their Effects on Blood Pressure and Blood Glucose
Objective To analyze the clinical efficacy of olanzapine,amisulapride combined with sitagliptin and met-formin in the treatment of senile schizophrenia with diabetes mellitus and its effects on blood pressure and blood glu-cose.Methods The clinical data of 58 cases of elderly patients with schizophrenia combined with diabetes mellitus ad-mitted to Shouning County Psychiatric Hospital from January to December 2021 were retrospectively selected,and were divided them into the control group and observation group in accordance with the different treatment methods,each of which consisted of 29 cases.Both groups were given combined treatment with olanzapine and amisulapride.On this basis,metformin was used in the control group and sitagliptin metformin in the observation group.The treat-ment results between two groups were compared.Results The total effective rate of treatment in the observation group was 93.11%,higher than 72.41%in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in clinical indicators between the two groups(P>0.05).After treatment,the observation group's clinical indicators were better than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Olanzapine,amisulapride combined with sitagliptin and metformin in the treatment of elderly patients with schizophrenia and diabetes have excellent effects,which can effectively stabi-lize blood glucose level.
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