Objective To explore the value of the combined application of psychological care and exercise therapy in the care of gestational diabetes mellitus.Methods 70 cases of gestational diabetes mellitus admitted to Qingyang People's Hospital from January 2020 to August 2023 were selected as study objects and were divided into the refer-ence group and the study group according to the coin tossing method,with 35 cases in each group.The reference group was given routine basic nursing intervention,and simple psychological nursing intervention was carried out dur-ing the period.The study group strengthened psychological nursing on the basis of the reference group and cooperated with exercise therapy intervention.The scores of bad mood,blood glucose level and quality of life were compared be-tween the two groups.Results After nursing,the anxiety,depression score,blood glucose level and quality of life of the study group were better than those of the reference group,and the differences were statistically significant(all P<0.05).Conclusion Gestational diabetes mellitus patients who receive clinical psychological care and exercise therapy intervention can obtain significant improvement in bad mood,blood glucose level and quality of life.