首页|胰岛素不同给药方式在ICU糖尿病酮症酸中毒患者治疗中应用的效果分析

胰岛素不同给药方式在ICU糖尿病酮症酸中毒患者治疗中应用的效果分析

Effect of Different Administration Modes of Insulin in ICU Patients with Diabetic Ketoacidosis

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目的 分析胰岛素不同给药方式在ICU糖尿病酮症酸中毒患者治疗中应用的效果.方法 选取2021年6月—2023年5月在晋江市医院ICU治疗的72例糖尿病酮症酸中毒患者,用随机数表法将其分为两组,各36例.对照组多次静脉滴注小剂量胰岛素治疗,观察组微量输液泵持续泵入胰岛素治疗,对比两组指标、疗效、不良反应发生率.结果 观察组症状恢复速度快于对照组,胰岛素用量低于对照组,差异有统计学意义(P均<0.05).治疗前两组血糖水平对比,差异无统计学意义(P>0.05),观察组治疗后血糖水平低于对照组,差异有统计学意义(P<0.05).观察组临床疗效高于对照组,不良反应发生率低于对照组,差异有统计学意义(P均<0.05).结论 微量(11 mg)输液泵持续泵入在ICU治疗的糖尿病酮症酸中毒患者治疗中应用的效果较为显著,有效改善患者临床症状,降低血糖水平,减少不良反应的发生率.
Objective To analyze the effect of different administration modes of insulin in ICU patients with diabetic ketoacidosis.Methods A total of seventy-two patients with diabetic ketoacidosis treated in the ICU of Jinjiang Hospi-tal from June 2021 to May 2023 were divided into two groups with thirty-six cases each by random table method.The control group was treated with low doses of insulin intravenously for several times,and the observation group was treated with insulin continuously by micro infusion pump.The inter-group indexes,efficacy and incidence of adverse reactions were compared.Results The recovery rate of symptoms in observation group was faster than that in control group,and the dosage of insulin was lower than that in control group,the differences were statistically significant(both P<0.05).There was no significant difference in blood glucose level between the two groups before treatment(P>0.05),and the blood glucose level in the observation group was lower than that in the control group after treatment,the differ-ence was statistically significant(P<0.05).The clinical efficacy of observation group was higher than that of control group,and the incidence of adverse reactions was lower than that of control group,the differences were statistically sig-nificant(P<0.05).Conclusion The application of micro infusion pump(11 mg)continuously in the treatment of dia-betic ketoacidosis patients treated in ICU has a significant effect,effectively improving clinical symptoms of patients,reducing blood glucose levels,and reducing the incidence of adverse reactions,which is worthy of promotion and ap-plication in clinical treatment.

InsulinDifferent modes of administrationICUDiabetes mellitusKetoacidosisTherapeutic effect

蔡婷茹、吴珊蓉、胡晓红

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晋江市医院,福建泉州 362200

胰岛素 不同给药方式重症监护 糖尿病 酮症酸中毒 治疗效果

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(4)
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