Objective To analyze the efficacy of dapagliflozin in treating type 2 diabetic nephropathy in the elderly and its effect on renal function.Methods A total of 68 patients with Diabetic Kidney Disease(DKD)in Siyang Kangda Hospital from June 2022 to June 2023 were selected.All patients are divided into daglipzin group and metformin group by odd-even grouping method,with 34 patients in each group.The metformin group was given metformin sustained-release tablets,and the dagaglizin group was given dagaglizin.Fasting plasma glucose(FPG),two hours postprandial blood glucose(2 hPG),serum creatinine(Scr)levels and total effective rate were compared between the two groups.Results The total effective rate of daglipzin group was significantly higher than that of metformin group,and the difference was statistically significant(P<0.05).After intervention,FPG,2 hPG and Scr in two groups were significantly ameliorated compared with those before intervention,and all indexes in Daglipzin group were better than those in metformin group,the differences were statistically significant(all P<0.05).Conclusion The efficacy of dapa-gliflozin in the treatment of elderly DKD is remarkable,which can significantly reduce the patients'blood glucose level and improve the renal function.
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