Evaluation of the Effectiveness and Efficacy of Dapagliflozin Combined with Beraprost Sodium in the Treatment of Patients with Peripheral Neu-ropathy in Type 2 Diabetes Mellitus
Objective To investigate the effect and efficiency of dapagliflozin combined with beraprost sodium in the treatment of patients with peripheral neuropathy in type 2 diabetes mellitus.Methods A total of 88 patients with type 2 diabetic peripheral neuropathy from Shishi General Hospital from September 2021 to October 2023 were selected for this study.They were divided by lot method.The control group(44 cases)was treated with beprost sodium,while the observation group(44 cases)was treated with dagaglizin and beprost sodium,and the blood glucose,conduction speed,clinical efficacy and adverse reactions of the two groups were compared.Results After 4 weeks of treatment,all blood glucose levels in the observation group were lower than those in the control group,all nerve conduction veloci-ties were higher than those in the control group,and the clinical treatment effectiveness was higher than that in the control group,the difference was statistically significant(all P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Dapagliflozin and beraprost so-dium combination can effectively treat type 2 diabetic peripheral neuropathy,with a significant decrease in blood glu-cose,significantly accelerated nerve conduction velocity,with fewer adverse reactions.
Type 2 diabetes mellitus peripheral neuropathyDapagliflozinBeraprost sodiumBlood glucoseEffec-tive rateAdverse reaction