血清C肽与血糖检测结合检验诊断糖尿病的准确性分析
Accuracy Analysis of Serum C-peptide Combined with Blood Glucose De-tection in Diagnosis of Diabetes Mellitus
史伟强 1黄艺虹 1陈腾忆 1叶伟林1
作者信息
- 1. 福州市第二医院检验科,福建福州 350007
- 折叠
摘要
目的 分析血清C肽与血糖检测结合检验诊断糖尿病的准确性.方法 选取2021年5月—2022年5月福州市第二医院就诊的100例糖尿病患者,纳入到分析组中,另选取同时期就诊的107例健康体检者,纳入到对照组中.对其共同进行糖尿病诊断,分析血清C肽、血糖检测、联合诊断结果.结果 分析组患者血清C肽低于对照组,空腹血糖、餐后2 h血糖、糖化血红蛋白水平均显著高于对照组,差异有统计学意义(P均<0.05).经血清C肽检测,阳性102例,阴性105例,其中82例为糖尿病患者;糖化血红蛋白检测出阳性102例,阴性105例,其中80例为糖尿病患者;联合检测方式中阳性102例,阴性105例,其中100例为糖尿病患者.联合检测对糖尿病患者诊断特异度、灵敏度及准确度水平均显著高于单一检测方式,差异有统计学意义(P均<0.05).结论 血清C肽与血糖检测结合检验诊断糖尿病,利于诊断准确度及诊断效能的提升.
Abstract
Objective To analyze the accuracy of serum C-peptide combined with blood glucose detection in the diag-nosis of diabetes.Methods A total of one hundred patients with diabetes who were treated in Fuzhou Second Hospital from May 2021 to May 2022 were selected and included in the analysis group,and one hundred and seven healthy physical examination subjects were selected at the same period to be included in the control group.They were jointly diagnosed of diabetes.The laboratory indicators,serum C-peptide,blood glucose test,combined diagnosis results were analysed.Results Serum C-peptide in analysis group was lower than that in control group,fasting blood glucose,2 h postprandial blood glucose and glycated hemoglobin levels were significantly higher than those in control group,and the difference was statistically significant(all P<0.05).Serum C-peptide test showed 102 positive cases and 105 negative cases,82 of which were diabetic patients.HbA1c was detected in 102 positive cases and 105 negative cases,80 of which were diabetic patients.A total of 102 positive cases and 105 negative cases were detected by the com-bined test,100 of which were diabetic patients.The diagnostic specificity,sensitivity and accuracy of diabetes pa-tients under the combined detection method were significantly higher than those under the single detection method,and the difference was statistically significant(all P<0.05).Conclusion The combination of serum C-peptide and blood glucose detection in the diagnosis of diabetes is conducive to the improvement of diagnostic accuracy and diag-nostic efficiency.
关键词
血清C肽/血糖检测/糖尿病/诊断/效果Key words
Serum C-peptide/Blood glucose detection/Diabetes mellitus/Diagnosis/Effect引用本文复制引用
基金项目
福州市卫生健康中青年科学研究项目(榕卫科技[2021]5号)
出版年
2024
NETL
NSTL
万方数据