首页|参苓白术散加减方治疗糖尿病性白内障术后黄斑水肿的临床疗效

参苓白术散加减方治疗糖尿病性白内障术后黄斑水肿的临床疗效

Clinical Effect of Shenling Baizhu Powder on Postoperative Macular Edema of Diabetic Cataract

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目的 探讨参苓白术散加减方治疗糖尿病性白内障术后黄斑水肿的临床优势.方法 回顾性选取2022年1-12月常德市第一中医医院的20例(20只眼)成年白内障术后糖尿病性黄斑水肿患者的临床资料,依据治疗方案的不同分为两组,其中涵盖治疗组(10例患者,10只眼)、对照组(10例患者,10只眼).对照组患者采用玻璃体腔注射康柏西普治疗,治疗组患者为玻璃体腔注射康柏西普加用参苓白术散加减方治疗,对比两组患者的相关指标,包括中医证候积分、黄斑中心凹视网膜厚度(Central Macular Thickness,CMT)、最佳矫正视力(Best Corrected Visual Acuity,BCVA).结果 治疗前,两组患者的中医证候积分、CMT、BCVA比较,差异无统计学意义(P均>0.05).治疗1个月后,治疗组中医证候积分低于对照组,BCVA优于对照组,CMT小于对照组,差异有统计学意义(P均<0.05).结论 参苓白术散加减方治疗糖尿病性白内障术后黄斑水肿,具有显著的临床优势,有较好的安全性以及远期疗效,可以有效改善白内障患者的视力、视觉神经系统.
Objective To explore the clinical advantages of Shenling Baizhu Powder in the treatment of postoperative macular edema after diabetic cataract.Methods The clinical data of 20 cases(20 eyes)of adult patients with diabetic macular edema after cataract surgery in the First Hospital of Traditional Chinese Medicine of Changde City from Janu-ary to December 2022 were retrospectively selected and were divided into two groups according to different treatment plans,including the treatment group(10 patients,10 eyes)and the control group(10 patients,10 eyes).The control group was treated with intravitreal injection of comcaercept,while the treatment group was treated with intravitreal in-jection of comcaercept plus Shenling Baizhu Powder.The relevant indexes of the two groups were compared,including Traditional Chinese Medicine(TCM)syndrome score,central macular thickness(CMT),best corrected visual acuity(BCVA).Results Before treatment,there were no significant differences in TCM syndrome scores,CMT and BCVA be-tween the two groups(all P>0.05).After 1 month of treatment,the TCM syndrome score of the treatment group was lower than that of the control group,BCVA was better than that of the control group,and CMT was smaller than that of the control group,and the differences were statistically significant(all P<0.05).Conclusion Shenling Baizhu Powder has significant clinical advantages in the treatment of macular edema after diabetic cataract surgery,has good safety and long-term efficacy,and can effectively improve the vision and visual nervous system of cataract patients.

Shenlingbaizhu PowderComcaerceptCataract surgeryDiabetic macular edema

李为、黄凌飞、翦可馨

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常德市第一中医医院眼科,湖南常德 415000

参苓白术散 康柏西普 白内障术后 糖尿病性黄斑水肿

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(5)
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