尿微量白蛋白与尿肌酐比值对糖尿病肾病的早期诊断价值
Early Diagnosis of Diabetic Nephropathy by Urine Microalbumin Creati-nine Ratio
郭美玲 1树琳 1李进 1张晶晶1
作者信息
- 1. 建湖县第三人民医院检验科,江苏建湖 224700
- 折叠
摘要
目的 本研究旨在探讨尿微量白蛋白与尿肌酐比值(Urine Microalbumine Creatinine ratio,UACR)在糖尿病肾病(Diabetic Kidney Disease,DKD)早期诊断中的价值.方法 选取2023年4-11月于建湖县第三人民医院就诊的62例疑似患有DKD的2型糖尿病(Diabetes Mellitus Type 2,T2DM)的患者为研究对象.分别采用以尿微量白蛋白(Urinary Microalbumin,UMA)、尿肌酐(Urine Creatinine,UCr)和UACR为标准的检测方法检测患有早期糖尿病肾病的人数,以肾穿刺活检为检测早期DKD的金标准,将检测结果与金标准相比较,计算三种检测方法的诊断效能值.结果 检测性能方面,UACR在早期诊断时的灵敏度、准确度均显著高于UMA和UCr单独检测,差异有统计学意义(P均<0.05).结论 监测UACR的变化有助于DKD的早期诊断.
Abstract
Objective The aim of this study was to investigate the value of urinary microalbumine creat-inine ratio(UACR)in the early diagnosis of diabetic kidney disease(DKD).Methods 62 patients with type 2 diabetes mellitus type 2(T2DM)suspected of suffering from DKD who attended Jianhu Third People's Hospital from April to November 2023 were selected as study subjects.The number of patients with early diabetic nephropathy was detected using the standardized tests of urinary microalbumin(UMA),urinary creatinine(UCr)and UACR,respectively,and renal punc-ture biopsy was used as the gold standard for detecting early DKD.The results were compared with the gold standard and the diagnostic efficacy values of the three assays were calculated.Results In terms of detection performance,the sensitivity and accuracy of UACR in early diagnosis were significantly higher than that of UMA and UCr alone,and the differences were statistically significant(both P<0.05).Conclusion Monitoring the changes of UACR is helpful for the early diagnosis of DKD.
关键词
糖尿病肾病/尿微量白蛋白与尿肌酐比值/早期诊断价值/检测效能Key words
Diabetic kidney disease/Urine microalbumine creatinine ratio/Early diagnostic value/Detection efficacy引用本文复制引用
出版年
2024
NETL
NSTL
万方数据