首页|右美托咪定在合并手术治疗的2型糖尿病患者中的应用及对其血糖水平的影响

右美托咪定在合并手术治疗的2型糖尿病患者中的应用及对其血糖水平的影响

Effect of Dexmedetomidine on Blood Glucose Level in Patients with Type 2 Diabetes undergoing Surgical Treatment

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目的 探讨右美托咪定在合并手术治疗的2型糖尿病患者全身麻醉中的应用及对其血糖水平的影响.方法 选择2020年5月—2023年5月于泉州市泉港区医院行手术治疗的70例2型糖尿病患者为研究对象,以随机数表法分为观察组(n=35)与对照组(n=35).对照组行全麻,观察组采用右美托咪定联合全麻.比较两组患者血流动力学、血糖水平及麻醉药物安全性.结果 两组患者麻醉前平均动脉压(Mean Arterial Pres-sure,MAP)、心率、血糖水平以及麻醉药物安全性比较,差异无统计学意义(P均>0.05).对照组插管时、切皮时、拔管时的MAP、心率和血糖水平均高于麻醉前,并且高于观察组,差异有统计学意义(P均<0.05).结论 右美托咪定在合并手术治疗的2型糖尿病患者全身麻醉中具有较高的应用价值,利于维持血流动力学稳定,预防血糖水平升高,且安全性较高.
Objective To investigate the application of dexmedetomidine in general anesthesia and the influence of blood glucose level in type 2 diabetes patients with surgery.Methods 70 patients with type 2 diabetes who underwent surgical treatment in Quangang District Hospital of Quanzhou City from May 2020 to May 2023 were selected as the study objects and divided into observation group(n=35)and control group(n=35)by random number table method.The control group received general anesthesia,and the observation group received dexmedetomidine combined with general anesthesia.Hemodynamics,blood glucose level and safety of anesthetic drugs were compared between the two groups.Results There was no statistically significant difference in mean arterial pressure(MAP),heart rate,blood glu-cose level before anesthesia and safety of anesthetic drugs between the two groups(all P>0.05).The MAP,heart rate and blood glucose levels at intubation,skin incision and extubation in the control group were higher than those before anesthesia,and higher than those in the observation group,the differences were statistically significant(all P<0.05).Conclusion Dexmedetomidine has a high application value in general anesthesia of type 2 diabetes patients combined with surgery,which is conducive to maintaining hemodynamic stability and preventing elevated blood glucose level,and has a high safety.

Type 2 diabetesDexmedetomidineGeneral anesthesiaBlood glucose level

陆彬彬、詹启川、庄伟彬

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泉州市泉港区医院麻醉科,福建泉州 362802

泉州市泉港区医院检验科,福建泉州 362802

2型糖尿病 右美托咪定 全身麻醉 血糖水平

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(5)
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