Study on the Improvement of Immune Index and Pregnancy Outcome of Gestational Diabetes Mellitus with Insulin Combined with Individualized Nutrition Therapy
Objective To analyze the effect of insulin combined with individualized nutrition therapy on immune in-dex and pregnancy outcome in patients with gestational diabetes.Methods A total of 78 patients with gestational dia-betes mellitus from April 2022 to June 2023 admitted to Putian University Affiliated Hospital were selected as the study objects.The patients were randomly sorted by Excel table,and were diviede into the control group(routine treat-ment)and the observation group(insulin combined with individualized nutrition treatment)according to the the odd and even number of serial numbers with 39 cases in each group.The nutritional level,islet index,blood glucose index and pregnancy outcome of two groups were analyzed.Results Before treatment,there were no significant differences in blood glucose level and glycosylated hemoglobin A1c level between the two groups(both P>0.05).After treatment,the indexes above in the observation group were lower than those in the control group,the differences were statistically sig-nificant(both P<0.05).Hemoglobin,albumin and transferrin level of the observation group were higher than those of the control group after treatment,the differences were statistically significant(all P<0.05).After treatment,the insulin resistance index of observation group was lower than that of control group,and the function index of islet β cell was higher in the observation group than that of control group,the differences were statistically significant(both P<0.05).The incidence rate of adverse pregnancy outcome in observation group was lower than that in control group,the differ-ence was statistically significant(P<0.05).Conclusion The combination treatment of insulin and individualized nutri-tion for gestational diabetes patients can improve the level of blood glucsoe,nutrition and islet function,and improve the pregnancy outcome.
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