Objective To investigate the effect of multiple subcutaneous injection and continuous subcutaneous infu-sion of insulin in the treatment of type 1 diabetes in children.Methods A total of 90 children with type 1 diabetes re-ceived by the Zibo Maternal and Child Health Hospital from January 2018 to October 2023 were selected as the study objects,and they were divided into two groups with 45 cases in each group by computer random number and even number.The control group received multiple subcutaneous injections of insulin,and the observation group received continuous subcutaneous infusion of insulin.Blood glucose level,blood glucose recovery time,insulin dosage and ad-verse events were compared between the two groups.Results After treatment for 3 and 6 months,the fasting plasma glucose,2 h postprandial blood glucose,glycosylated hemoglobin A1c levels decreased in both groups,the observation group was lower than the control group,and the differences were statistically significant(all P<0.05).The blood glu-cose recovery time in the observation group was shorter than that in the control group,the average dosage of insulin and the frequency of hypoglycemia were less,and the differences were statistically significant(all P<0.05).The inci-dence rate of adverse events in the observation group was 4.44%,lower than 28.89%in the control group,and the dif-ference was statistically significant(χ2=9.680,P<0.05).Conclusion In the treatment of type 1 diabetes in children,continuous subcutaneous insulin infusion can improve the blood glucose control effect,stabilize the blood glucose level for a long time,and the blood glucose recovery is rapid,reducing the amount of insulin to avoid the occurrence of related adverse events,and the efficacy and safety are superior to multiple subcutaneous insulin injection,the imple-ment value is significant.