探讨胰岛素泵短期强化治疗围绝经期妇女糖尿病对糖代谢指标的影响
Effects of Short-term Intensive Insulin Pump Therapy on Glucose Metabo-lism Indexes in Perimenopausal Women with Diabetes
赵君丽 1栾允峰2
作者信息
- 1. 包头市中心医院妇产科,内蒙古包头 014040
- 2. 内蒙古自治区人民医院妇产科,内蒙古呼和浩特 010010
- 折叠
摘要
目的 探究围绝经期妇女糖尿病采用胰岛素泵短期强化治疗的效果.方法 选取2021年4月—2023年11月包头市中心医院收治的46例糖尿病患者为研究对象,均为围绝经期女性,按照随机数表法分为两组,每组23例.对照组行基础治疗+胰岛素皮下治疗,研究组采用胰岛素泵短期强化治疗,对比两组血糖、治疗指标、降糖有效率和低血糖发生率.结果 治疗后,研究组空腹血糖、餐后2 h血糖以及糖化血红蛋白水平低于对照组,差异有统计学意义(P均<0.05);研究组治疗后血糖达标时间更快,胰岛素用量低于对照组,差异有统计学意义(P均<0.05);与对照组相比,研究组降糖有效率高,低血糖发生率更低,差异有统计学意义(P均<0.05).结论 围绝经期糖尿病采用短期强化胰岛素泵治疗,起效快、及早调节血糖代谢,合理设置胰岛素用量,加速胰岛功能恢复.
Abstract
Objective To explore the effect of short-term intensive treatment with insulin pump in perimenopausal women with diabetes.Methods From April 2021 to November 2023,46 diabetic patients were selected as the study objects from Baotou Central Hospital,all of whom were perimenopausal women.They were divided into 2 groups by random number table method,with 23 cases in each group.The control group received basic therapy+insulin subcu-taneous therapy.The study group received short-term intensive treatment with insulin pump.Blood glucose,treatment indicators and the hypoglycemic effective rate and the incidence of hypoglycemia were compared between two groups.Results After treatment,fasting blood glucose,2 h postprandial blood glucose and glycation level in the study group were lower than those in the control group,the differences were statistically significant(all P<0.05).After treatment,the total blood glucose reached the standard faster in the study group,and the insulin dosage was also lower than that in the control group,the differences were statistically significant(both P<0.05).In the study group,the hypoglycemic effective rate was higher,and the incidence of hypoglycemia was lower than the control group,the differences were sta-tistically significant(both P<0.05).Conclusion Perimenopausal diabetes is treated with short-term intensive insulin pump,which has quick effect,early adjustment of blood glucose metabolism,reasonable setting of insulin dosage,and accelerating the recovery of islet function.
关键词
胰岛素泵/短期强化治疗/围绝经期糖尿病/糖代谢指标/降糖有效率Key words
Insulin pump/Short-term intensive treatment/Perimenopausal diabetes mellitus/Glucose metabolism in-dex/Hypoglycemic effective rate引用本文复制引用
出版年
2024
NETL
NSTL
万方数据