首页|加强型降糖治疗联合牙周基础治疗对2型糖尿病合并中重度慢性牙周炎患者血糖及炎性因子水平的影响

加强型降糖治疗联合牙周基础治疗对2型糖尿病合并中重度慢性牙周炎患者血糖及炎性因子水平的影响

Effect of Intensive Hypoglycemic Therapy Combined with Periodontal Basal Therapy on Blood Glucose and Inflammatory Factor Levels in Pa-tients with Type 2 Diabetes Mellitus Combined with Moderate-to-severe Chronic Periodontitis

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目的 探究加强型降糖治疗联合牙周基础治疗对2型糖尿病合并中重度慢性牙周炎患者血糖及炎性因子水平的影响.方法 选取德化县医院于2020年1月—2023年1月期间接收的62例2型糖尿病合并中重度慢性牙周炎患者作为研究对象,按照红蓝球法随机分为两组,每组31例.对照组采取糖尿病基础治疗联合牙周基础治疗,观察组在对照组的基础上采取加强型降糖治疗,对比两组治疗后血糖水平、炎性因子水平及牙周指数.结果 治疗后,观察组血糖控制水平优于对照组,差异有统计学意义(P<0.05);观察组各项炎性因子水平均低于对照组,差异有统计学意义(P均<0.05);观察组各项牙周指数均低于对照组,差异有统计学意义(P均<0.05).结论 针对2型糖尿病合并中重度慢性牙周炎患者采取加强型降糖治疗联合牙周基础治疗有助于控制血糖水平,并降低炎性因子水平,对于改善牙周指数效果更佳.
Objective To investigate the effects of intensive hypoglycemic therapy combined with periodontal basic therapy on blood glucose and inflammatory factor levels in patients with type 2 diabetes mellitus combined with moderate-to-severe chronic periodontitis.Methods Sixty-two patients with type 2 diabetes mellitus combined with moderate-to-severe chronic periodontitis admitted to Dehua County Hospital between January 2020 and January 2023 were selected as the study subjects,and were randomly divided into two groups according to the red and blue ball method,with 31 cases in each group.The control group took diabetes basic treatment combined with periodontal basic treatment,and the observation group took intensive hypoglycemic treatment on the basis of the control group.The blood glucose level,inflammatory factor level and periodontal index after treatment in the two groups were compared.Results After treatment,the blood glucose control level of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The levels of inflammatory factors in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).All periodontal indices of the observation group were lower than those of the control group,and the differences were statis-tically significant(all P<0.05).Conclusion For patients with type 2 diabetes mellitus combined with moderate-to-severe chronic periodontitis,the use of intensive hypoglycemic therapy combined with periodontal basic therapy can help to control blood glucose levels and reduce the level of inflammatory factors,which has a better effect on improv-ing the periodontal index.

Type 2 diabetes mellitusModerate-to-severe chronic periodontitisPeriodontal basic therapyIntensive hypoglycemic therapyInflammatory factorPeriodontal indexBlood glucose level

林瑞坤、赖丽清、詹宗暧

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泉州市德化县医院口腔科,福建泉州 362501

三明市尤溪县总医院口腔科,福建三明 365100

2型糖尿病 中重度慢性牙周炎 牙周基础治疗 加强型降糖治疗 炎性因子 牙周指数 血糖水平

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(7)
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