Objective To study the efficacy of dapagliflozin combined with insulin intensive therapy in the treatment of type 2 diabetes patients.Methods A total of 88 patients with type 2 diabetes admitted to Tengzhou Workers'Hospi-tal from November 2022 to November 2023 were selected as the study subjects.They were divided into two groups by coin method,44 cases in each group.The monotherapy group received intensive insulin therapy,and the combined group received intensive insulin therapy combined with dagaglizin.The treatment effect of two groups were compared.Results After treatment,the blood glucose index of combination group was lower than that of monotherapy group,and the difference was statistically significant(P<0.05).Compared with the monotherapy group,the index of blood glucose fluctuation in the combined group after treatment was smaller,and the difference was statistically significant(P<0.05).Compared with the monotherapy group,the combined group had lower homeostasis model assessment of insulin resis-tance index,higher homeostasis model assessment of islet β cell function and fasting insulin,and the differences were statistically significant(all P<0.05).Conclusion The combination of dapagliflozin and insulin intensive therapy in the treatment of type 2 diabetes patients can achieve ideal results and improve blood glucose index.
Type 2 diabetesDapagliflozinInsulinIntensive treatmentBlood glucose index
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NSTL
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