胰激肽原酶治疗糖尿病周围神经病变的临床效果探究
Investigation of the Clinical Effect of Pancreatic Kininogenase in the Treat-ment of Diabetic Peripheral Neuropathy
周娴 1刘小松1
作者信息
- 1. 宜兴市官林医院内分泌科,江苏宜兴 214200
- 折叠
摘要
目的 探究糖尿病周围神经病变患者使用胰激肽原酶进行治疗的临床效果.方法 选取2021年1月—2023年12月宜兴市官林医院收治的135例糖尿病周围神经病变患者为研究对象,应用奇偶数法分为对照组(65例)、研究组(70例).对照组使用硫辛酸注射液,研究组使用胰激肽原酶.对比两组临床疗效、症状改善时间、神经功能、神经传导速度.结果 研究组相比于对照组临床疗效更好,研究组疼痛、麻木及感觉异常改善时间短于对照组,差异有统计学意义(P均<0.05).治疗后,研究组感觉功能、神经症状及神经反射优于对照组,差异有统计学意义(P均<0.05).治疗后,研究组神经传导速度快于对照组,差异有统计学意义(P<0.05).结论 使用胰激肽原酶可显著改善糖尿病周围神经病变症状,提高神经功能,神经传导速度加快,临床效果显著.
Abstract
Objective To investigate the clinical effect of pancreatic kininogenase in the treatment of diabetic periph-eral neuropathy.Methods A total of 135 cases of diabetic peripheral neuropathy patients admitted to Yixing Guanlin Hospital from January 2021 to December 2023 were selected as the study objects,and divided into 65 cases in the con-trol group and 70 cases in the study group by applying the odd-even number method.The control group used lipoic acid injection.The study group used pancreatic kininogenase.Clinical efficacy,symptom improvement time,nerve function and nerve conduction velocity were compared between the two groups.Results Clinical efficacy was better in the study group compared to the control group.The improvement time of pain,numbness and sensory abnormality in the study group was shorter than that in the control group,and the differences were statistically significant(all P<0.05).After treatment,the study group's sensory function,neurological symptoms and nerve reflexes were better than those of the control group,and the differences were statistically significant(all P<0.05).After treatment,the nerve conduction velocity of the study group was faster than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The use of pancreatic kininogenase can significantly improve the symptoms of diabetic peripheral neuropathy,improve nerve function,nerve conduction velocity accelerated,the clinical effect is remarkable.
关键词
糖尿病周围神经病变/胰激肽原酶/神经功能/神经传导速度Key words
Diabetic peripheral neuropathy/Pancreatic kininogenase/Nerve function/Nerve conduction velocity引用本文复制引用
出版年
2024
NETL
NSTL
万方数据