Objective To investigate the clinical efficacy of miglitol and glipizide in the treatment of type 2 diabetes mellitus and its influence on blood glucose level.Methods A total of eighty-four patients with type 2 diabetes admit-ted to the Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine from October 2021 to Oc-tober 2023 were selected as the study objects,and they were divided into two groups according to random number table method,with forty-two patients in each group.The control group was given glipizide monotherapy,and the obser-vation group was given miglitol plus glipizide.The clinical efficacy,blood glucose control,islet function and drug safety were compared between the two groups.Results The total effective rate of observation group(95.24%)was higher than that of control group(80.95%),and the difference was statistically significant(χ2=4.086,P=0.043).After treatment,the blood glucose control indexes and islet function indexes of the observation group were lower than those of the control group,and the differences were statistically significant(both P<0.05).There was no significant differ-ence in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of miglitol and glipizide can significantly improve the therapeutic effect of type 2 diabetes patients,regulate blood glucose and islet function more effectively,and ensure the safety of medication.
Type 2 diabetes mellitusMiglitolGlipizideClinical effectBlood glucose level
维普
万方数据
