首页|降糖舒胶囊结合西格列汀对老年T2DM患者糖脂代谢及胰岛功能的影响

降糖舒胶囊结合西格列汀对老年T2DM患者糖脂代谢及胰岛功能的影响

Effects of Jiangtangshu Capsule Combined with Sitagliptin on Glucose and Lipid Metabolism and Islet Function in Elderly Patients with T2DM

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目的 探究老年2型糖尿病(Type 2 Diabetes Mellitus,T2DM)患者采用降糖舒胶囊结合西格列汀的临床疗效.方法 选取2022年1月—2023年12月龙岩人民医院收治的80例T2DM患者为研究对象,依据随机数表法分为两组,各40例.对照组采用磷酸西格列汀治疗,观察组采用磷酸西格列汀+降糖舒胶囊治疗.对比两组糖脂代谢水平、胰岛功能、炎性因子水平.结果 观察组各项糖脂代谢水平低于对照组,差异有统计学意义(P均<0.05).观察组各项胰岛功能均优于对照组,差异有统计学意义(P均<0.05).观察组各项炎性因子水平低于对照组,差异有统计学意义(P均<0.05).结论 在对老年T2DM治疗时,磷酸西格列汀联合降糖舒胶囊可改善糖脂代谢水平,提高胰岛素功能.
Objective To explore the clinical efficacy of Jiangtangshu capsule combined with sitagliptin in elderly pa-tients with type 2 diabetes mellitus(T2DM).Methods A total of eighty T2DM patients admitted to Longyan People's Hospital from January 2022 to December 2023 were selected as the study objects and divided into two groups with forty cases each according to random number table method.The control group was treated with sitagliptin phosphate,and the observation group was treated with sitagliptin phosphate+Jiangtangshu capsule.The levels of glucose and lipid metabolism,islet function and inflammatory factors were compared between the two groups.Results The levels of glucose and lipid metabolism in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The islet function levels of the observation group were better than those of the control group,and the differences were statistically significant(all P<0.05).The levels of inflammatory factors in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion In the treatment of elderly T2DM,sitagliptin phosphate combined with Jiangtangshu capsule can improve the level of glucose and lipid metabolism and improve insulin function.

ElderlyType 2 diabetes mellitusJiangtangshu capsuleSitagliptinInsulin function

谢靖、林燕、傅春梅

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龙岩人民医院药剂科,福建 龙岩 364000

老年 2型糖尿病 降糖舒胶囊 西格列汀 胰岛素功能

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(8)