Objective To analyze the effects of long-acting insulin on fasting plasma glucose(FPG)and 2-hour post-prandial plasma glucose(2 hPG)in type 2 diabetes mellitus patients.Methods A total of seventy-eight patients with type 2 diabetes admitted to Zhanhua District Second People's Hospital from July 2021 to July 2023 were selected as the study objects,and they were divided into the control group(oral hypoglycemic agents)and the study group(oral hypoglycemic agents+long-acting insulin)by random number table method,with thirty-nine cases each.Blood glucose index,islet cell function index and C-peptide level were compared between the two groups.Results FPG,2 hPG,glycosylated hemoglobin A1c and insulin resistance index in the study group were significantly lower than those in the control group,fasting insulin,islet β cell secretion index,fasting C-peptide and 2-hour postpran-dial C-peptide were significantly higher than those in control group,and the differences were statistically significant(all P<0.05).Conclusion On the basis of conventional oral hypoglycemic drugs,the addition of long-acting insulin therapy can improve the blood glucose control effect of type 2 diabetes and improve the function of islet cells.
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