糖尿病新世界2024,Vol.27Issue(8) :172-175.DOI:10.16658/j.cnki.1672-4062.2024.08.172

酮症酸中毒为首发症状的小儿糖尿病临床治疗效果研究

Clinical Treatment Effect of Pediatric Diabetes with Ketoacidosis as the First Symptom

谢祥恩 黄炳暖 廖爱萍
糖尿病新世界2024,Vol.27Issue(8) :172-175.DOI:10.16658/j.cnki.1672-4062.2024.08.172

酮症酸中毒为首发症状的小儿糖尿病临床治疗效果研究

Clinical Treatment Effect of Pediatric Diabetes with Ketoacidosis as the First Symptom

谢祥恩 1黄炳暖 1廖爱萍1
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作者信息

  • 1. 龙岩人民医院儿科,福建 龙岩 364000
  • 折叠

摘要

目的 探讨首发症状为酮症酸中毒的小儿糖尿病进行胰岛素静脉滴注的临床疗效.方法 选取2019年1月—2024年1月龙岩人民医院收治的首发症状为酮症酸中毒的80例患儿为研究对象,根据随机排列表法分为常规组(n=40,诺和灵R+诺和灵N)和研究组(n=40,诺和灵R+地特胰岛素).比较两组患儿治疗效果、血糖(空腹血糖、餐后2 h血糖)水平和并发症发生情况.结果 研究组住院时间、尿酮体消除时间和血pH值恢复时间均显著低于常规组,差异有统计学意义(P均<0.05).治疗后,两组患儿空腹血糖、餐后2 h血糖水平均较治疗前降低,且研究组低于常规组,差异有统计学意义(P均<0.05).研究组并发症总发生率(2.50%)低于常规组(20.00%),差异有统计学意义(χ2=4.507,P<0.05).结论 对首发症状为酮症酸中毒的小儿糖尿病患儿应用诺和灵R联合地特胰岛素治疗,其临床治疗效果较好,并能降低患儿血糖水平和并发症发生率.

Abstract

Objective To investigate the clinical effect of intravenous insulin infusion in children with diabetes melli-tus whose first symptom was ketoacidosis.Methods A total of eighty children with the first symptom of ketoacidosis admitted to Longyan People's Hospital from January 2019 to January 2024 were selected as the study objects,and they were divided into the conventional group(n=40,Novalurin R+Novalurin N)and the study group(n=40,Noval-urin R+Dieter's insulin)according to random order table method.The treatment effect,blood glucose levels(fasting blood glucose,2-hour postprandial blood glucose)and complications were compared between the two groups.Results The hospitalization time,urinary ketone body elimination time and blood pH recovery time in the study group were sig-nificantly lower than those in the conventional group,and the differences were statistically significant(all P<0.05).Af-ter treatment,fasting blood glucose and 2-hour postprandial blood glucose levels in two groups were decreased com-pared with those before treatment,and those in the study group were lower than the conventional group,and the differ-ences were statistically significant(both P<0.05).The total incidence of complications in the study group(2.50%)was lower than that in the conventional group(20.00%),and the difference was statistically significant(χ2=4.507,P<0.05).Conclusion The application of Novolin R combined with Dieter's insulin to pediatric diabetic children whose first symptom is ketoacidosis has a better clinical therapeutic effect and reduces the children's blood glucose level and the incidence of complications.

关键词

小儿糖尿病/血糖水平/并发症/酮症酸中毒

Key words

Pediatric diabetes mellitus/Blood glucose levels/Complications/Ketoacidosis

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出版年

2024
糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
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