首页|高通量血液透析联合血液灌流治疗糖尿病肾病维持性血液透析的疗效分析

高通量血液透析联合血液灌流治疗糖尿病肾病维持性血液透析的疗效分析

Effect of High Throughput Hemodialysis Combined with Hemoperfusion on Maintenance Hemodialysis of Diabetic Nephropathy

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目的 评估糖尿病肾病患者维持性血液透析期间选用高通量血液透析联合血液灌流模式的治疗效果.方法 回顾性选取2021年3月—2023年9月福建省南平同道仁爱医院肾内科接受维持性血液透析治疗的60例糖尿病肾病患者的临床资料,按照治疗方法不同将其分为对照组、观察组,每组30例,对照组应用高通量血液透析,观察组应用高通量血液透析联合血液灌流,对比两组临床疗效.结果 治疗后,观察组各项肾功能水平优于对照组,微炎症状态各指标测定数值均低于对照组,差异有统计学意义(P均<0.05).观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05).结论 糖尿病肾病患者予以其高通量血液透析联合血液灌流治疗具有突出效果,可减少并发症、改善机体微炎症状态以及促进肾功能恢复,有利于全面提高生活质量、降低病死率.
Objective To evaluate the treatment effect of high throughput hemodialysis combined with hemoperfusion during maintenance hemodialysis in diabetic nephropathy patients.Methods Clinical data of sixty patients with dia-betic nephropathy who received maintenance hemodialysis treatment in the Department of Nephrology of Nanping Tongdao Renai Hospital in,Fujian Province from March 2021 to September 2023 were retrospectively selected.Ac-cording to different treatment methods,and they were divided into control group and observation group,with thirty cases in each group.The control group was treated with high throughput hemodialysis,the observation group with high throughput hemodialysis combined with hemoperfusion,and the clinical efficacy of the two groups was compared.Results After treatment,the level of renal function in the observation group was better than that in the control group,and the measured values of microinflammatory status indexes were lower than those in the control group,and the dif-ferences were statistically significant(both P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion In diabetic nephropathy patients,high throughput hemodialysis combined with hemoperfusion has outstanding effects,which can reduce complications,improve the micro-inflammatory state of the body and promote the recovery of renal function,which is conducive to improving the overall quality of life and reducing mortality.

High throughput hemodialysisHemoperfusionDiabetic nephropathyMaintenance hemodialysis

陈刚

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福建省南平同道仁爱医院肾内科,福建 南平 353000

高通量血液透析 血液灌流 糖尿病肾病 维持性血液透析

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(8)