首页|阿卡波糖联合二甲双胍治疗老年糖尿病的疗效及安全性分析

阿卡波糖联合二甲双胍治疗老年糖尿病的疗效及安全性分析

Efficacy and Safety of Acarbose Combined with Metformin in the Treat-ment of Elderly Diabetes

扫码查看
目的 探讨阿卡波糖联合二甲双胍在老年糖尿病中的疗效及安全性.方法 选取2021年9月—2023年9月乌兰察布市第二医院收治的80例老年糖尿病患者为研究对象,依据随机数表法分为两组,每组40例.对照组给予二甲双胍治疗,观察组给予二甲双胍+阿卡波糖治疗.对比两组患者临床疗效、治疗前后血糖差异和不良反应发生情况.结果 观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05).治疗前,两组血糖水平比较,差异无统计学意义(P>0.05);治疗后,观察组血糖水平低于对照组,差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 在老年糖尿病患者治疗中联合应用阿卡波糖和二甲双胍,疗效更为确切,并可显著降低患者血糖水平,安全性较高.
Objective To explore the efficacy and safety of acarbose combined with metformin in elderly patients with diabetes.Methods A total of 80 elderly diabetic patients admitted to Ulanqab Second Hospital from September 2021 to September 2023 were selected as the study objects and divided into two groups according to random number table method,with 40 cases in each group.The control group was given metformin treatment,and the observation group was given metformin+acarbose treatment.The clinical efficacy,blood glucose difference before and after treatment and the occurrences of adverse reactions were compared between the two groups.Results The total effective rate of the ob-servation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Be-fore treatment,there was no significant difference in blood glucose level between the two groups(P>0.05).After treat-ment,the blood glucose level of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Acarbose combined with metformin is more effective in elderly patients with diabe-tes,and can significantly reduce the blood glucose level of patients with high safety.

Elderly diabetesAcarboseMetforminSecurity

宋晓芳

展开 >

乌兰察布市第二医院,内蒙古 乌兰察布 012000

老年糖尿病 阿卡波糖 二甲双胍 安全性

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
  • 10