首页|利拉鲁肽对超重2型糖尿病患者血糖水平及胰岛素抵抗的影响

利拉鲁肽对超重2型糖尿病患者血糖水平及胰岛素抵抗的影响

Effect of Liraglutide on Blood Glucose Level and Insulin Resistance in Overweight Type 2 diabetes Patients

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目的 分析利拉鲁肽在超重2型糖尿病患者治疗中对血糖、胰岛素抵抗、生活质量各方面的影响.方法 选取江苏省句容市人民医院于2018年1月—2023年12月收治的216例糖尿病患者为研究对象,以密闭信封法分为两组,各108例.两组均使用胰岛泵进行常规治疗,对照组使用二甲双胍治疗,研究组采用二甲双胍结合利拉鲁肽注射液治疗,两组均治疗3个月.对比两组血糖水平、胰岛功能、生活质量.结果 干预后,研究组血糖水平低于对照组,胰岛功能优于对照组,生活质量评分高于对照组,差异有统计学意义(P均<0.05).结论 利拉鲁肽治疗超重2型糖尿病,能够降低血糖水平,改善胰岛素抵抗,提升患者生活质量.
Objective To analyze the effects of liraglutide in the treatment of blood glucose,insulin resistance and quality of life in overweight patients with type 2 diabetes.Methods A total of 216 diabetic patients admitted to Jurong People's Hospital of Jiangsu Province from January 2018 to December 2023 were selected as the study objects and di-vided into two groups with 108 cases each by sealed envelope method.Both groups received conventional treatment with islet pump,the control group received treatment with metformin,and the study group received treatment with met-formin combined with Liraglutide injection.Both groups were treated for 3 months.Blood glucose level,islet function and quality of life were compared between the two groups.Results After the intervention,the blood glucose level of the study group was lower than that of the control group,the islet function was better than that of the control group,and the quality of life score was higher than that of the control group,and the differences were statistically significant(all P<0.05).Conclusion Liraglutide in the treatment of overweight type 2 diabetes can reduce blood sugar levels,im-prove insulin resistance,and improve the quality of life of patients.

LiraglutideType 2 diabetesBlood glucose levelsOverweightQuality of life

王莹、刘婷、张超

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江苏省句容市人民医院内分泌科,江苏 镇江 212400

江苏省句容市人民医院呼吸科,江苏 镇江 212400

利拉鲁肽 2型糖尿病 血糖水平 超重 生活质量

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
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