首页|阿卡波糖与二甲双胍治疗糖尿病的疗效研究

阿卡波糖与二甲双胍治疗糖尿病的疗效研究

Efficacy of Acarbose and Metformin in the Treatment of Diabetes

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目的 分析糖尿病应用阿卡波糖与二甲双胍治疗的有效性.方法 选取天津市滨海新区中医医院于2023年1月—2024年1月收治的90例糖尿病患者为研究对象,以掷骰子法分为两组,每组45例.对照组给予二甲双胍治疗,观察组给予阿卡波糖与二甲双胍治疗,比较两组的血糖指标、胰岛功能指标、血脂指标、不良反应发生率.结果 观察组治疗后三项血糖指标均低于对照组,差异有统计学意义(P均<0.05).观察组治疗后胰岛素分泌指数高于对照组,胰岛素抵抗指数低于对照组,差异有统计学意义(P均<0.05).观察组治疗后的两项血脂指标均低于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率相比,差异无统计学意义(P>0.05).结论 糖尿病应用阿卡波糖与二甲双胍治疗效果好,不仅可以改善血糖控制情况,还可以改善患者胰岛功能,临床应用价值高.
Objective To analyze the efficacy of acarbose and metformin in the treatment of diabetes.Methods A to-tal of 90 diabetic patients admitted to Tianjin Binhai New Area Hospital of Traditional Chinese Medicine from January 2023 to January 2024 were selected as the study objects.They were divided into two groups with 45 cases in each group by dice method.The control group was treated with metformin,while the observation group was treated with acarbose and metformin.The blood glucose index,islet function index,blood lipid index and the incidence of adverse reactions were compared between the two groups.Results The three indexes of blood glucose in the observation group were lower than those in the control group after treatment,and the differences were statistically significant(all P<0.05).After treatment,the insulin secretion index of the observation group was higher than that of the control group,and the insulin resistance index was lower than that of the control group,and the differences were statistically signifi-cant(both P<0.05).After treatment,the two indexes of blood lipid in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Acarbose and metfor-min are effective in the treatment of diabetes,which can not only improve blood glucose control,but also improve the function of pancreatic islets in patients with high application value.

DiabetesMetforminAcarboseIslet function

季子凯、王婷、李华颖

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天津市滨海新区中医医院外科,天津 300451

糖尿病 二甲双胍 阿卡波糖 胰岛功能

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
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