首页|强化血糖控制治疗肺结核合并糖尿病患者的效果及可行性分析

强化血糖控制治疗肺结核合并糖尿病患者的效果及可行性分析

Effect and Feasibility Analysis of Intensive Blood Glucose Control in The Treatment of Pulmonary Tuberculosis Patients with Diabetes

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目的 探究强化血糖控制对肺结核合并糖尿病患者的治疗效果.方法 选取2022年12月—2023年12月宿迁市传染病医院收治的68例肺结核合并糖尿病患者为研究对象,按照奇偶数法分为对照组(34例)、研究组(34例).对照组采取常规治疗,研究组采取强化血糖控制治疗.比较两组治疗总有效率、不良反应发生率、血糖指标及胰岛功能、血糖变异性指标.结果 研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).治疗后,研究组空腹血糖、餐后2 h血糖、糖化血红蛋白水平低于对照组,胰岛素分泌指数高于对照组,差异有统计学意义(P均<0.05).研究组空腹血糖变异系数低于对照组,全天血糖标准差低于对照组,血糖最大波动幅度小于对照组,差异有统计学意义(P均<0.05).结论 强化血糖控制方案对肺结核合并糖尿病的临床治疗效果显著,不良反应少,具有临床应用价值.
Objective To explore the therapeutic effect of intensive blood glucose control on patients with pulmonary tuberculosis complicated with diabetes.Methods A total of 68 patients with tuberculosis combined with diabetes ad-mitted to Suqian Infectious Disease Hospital from December 2022 to December 2023 were selected as the study ob-jects,and they were divided into control group(34 cases)and research group(34 cases)according to odd-even method.The control group received conventional treatment,and the study group received intensive blood glucose con-trol.The total effective rate,the incidence of adverse reactions,blood glucose index,islet function and blood glucose variability index were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no significant differ-ence in the incidence of adverse reactions between the two groups(P>0.05).After treatment,fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin levels in the study group were lower than those in the control group,and insulin secretion index was higher than those in the control group,and the differences were statistically sig-nificant(all P<0.05).The fasting blood glucose variation coefficient,the standard deviation of blood glucose through-out the day and the maximum fluctuation range of blood glucose in the study group were lower than those in the con-trol group,and the differences were statistically significant(all P<0.05).Conclusion Intensive blood glucose control program has significant clinical effect on pulmonary tuberculosis complicated with diabetes and less adverse reactions,and has clinical application value.

Pulmonary tuberculosisDiabetesStrengthen blood sugar controlBlood glucose levelsIslet function

王海丽

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宿迁市传染病医院感染科,江苏 宿迁 223800

肺结核 糖尿病 强化血糖控制 血糖水平 胰岛功能

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
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