首页|利拉鲁肽治疗2型糖尿病的回顾性分析

利拉鲁肽治疗2型糖尿病的回顾性分析

Retrospective Analysis of Liraglutide in the Treatment of Type 2 Diabetes Mellitus

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目的 评估2型糖尿病患者运用利拉鲁肽治疗的有效性.方法 回顾性选取2022年2月—2023年2月晋江市医院收治的98例2型糖尿病患者的临床资料,根据治疗方式不同分为两组,各49例,对照组选择二甲双胍治疗,研究组选择利拉鲁肽治疗,比较两组治疗总有效率、体重指数、腰围、腰臀比、空腹血糖、餐后 2 h血糖、糖化血红蛋白水平.结果 研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05).治疗后,研究组体重指数、腰围、腰臀比低于对照组,差异有统计学意义(P均<0.05).治疗后,研究组各项血糖水平均低于对照组,差异有统计学意义(P均<0.05).结论 2型糖尿病患者应用利拉鲁肽治疗具有较好的治疗作用,可以降低血糖、体重.
Objective To evaluate the efficacy of liraglutide therapy in patients with type 2 diabetes mellitus.Methods The clinical data of 98 patients with type 2 diabetes mellitus admitted to Jinjiang City Hospital from Febru-ary 2022 to February 2023 were retrospectively selected and divided into two groups according to different treatment methods,with 49 cases in each group.The control group was treated with metformin,while the study group was treated with liraglutide.The total effective rate,body mass index,waist circumference,waist-to-hip ratio,fasting plasma glucose,2-hour postprandial plasma glucose and glycated hemoglobin A1c levels were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,and the dif-ference was statistically significant(P<0.05).After treatment,the body mass index,waist circumference and waist-to-hip ratio in the study group were lower than those in the control group,and the differences were statistically signifi-cant(all P<0.05).After treatment,the blood glucose levels of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Treatment with liraglutide in pa-tients with type 2 diabetes mellitus has a good therapeutic effect,which can reduce blood glucose and body weight.

Type 2 diabetes mellitusLiraglutideWaist-to-hip ratioBlood glucose

李炳煌、黄佳宁、钟经纶

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晋江市医院(上海市第六人民医院福建医院)药学部,福建 晋江 362200

晋江市医院(上海市第六人民医院福建医院)采供科,福建 晋江 362200

2型糖尿病 利拉鲁肽 腰臀比 血糖

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
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