首页|硫辛酸联合替米沙坦对糖尿病肾病血糖水平及血流动力学的影响分析

硫辛酸联合替米沙坦对糖尿病肾病血糖水平及血流动力学的影响分析

Effects of Lipoic Acid Combined with Telmisartan on Blood Glucose Lev-els and Hemodynamics in Diabetic Nephropathy

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目的 分析硫辛酸与替米沙坦联合治疗糖尿病肾病的疗效以及对血糖水平、血流动力学的影响.方法 选取2021年6月—2023年6月蒙阴县人民医院收治的78例糖尿病肾病患者为研究对象,按照治疗药物的不同分为两组,各39例.对照组以替米沙坦治疗,研究组以硫辛酸+替米沙坦治疗,比较两组治疗前后的血糖水平、血流动力学、肾功能水平及用药安全性.结果 治疗后,两组血糖水平、肾血流动力学、肾功能水平均优于治疗前,且研究组优于对照组,差异有统计学意义(P均<0.05).研究组用药安全性高于对照组,但两组比较,差异无统计学意义(P>0.05).结论 糖尿病肾病使用硫辛酸与替米沙坦联合治疗有助于改善患者的血糖水平和肾血流动力学以及肾功能,且用药安全性良好.
Objective To analyze the therapeutic effect of the combination of lipoic acid and telmisartan in the treat-ment of diabetic nephropathy,as well as the impact on blood glucose levels and hemodynamics.Methods A total of 78 patients with diabetic nephropathy admitted to Mengyin County People's Hospital from June 2021 to June 2023 were selected as the research objects.According to the different treatment drugs,they were divided into two groups,with 39 cases in each group.Control group was treated with telmisartan,the study group was treated with lipoic acid+telmisartan,compared two groups before and after treatment of blood glucose levels,renal hemodynamic,renal func-tion,and drug safety.Results After treatment,the blood glucose level,renal hemodynamics and renal function of the two groups were better than those before treatment,and the study group was better than the control group,and the dif-ferences were statistically significant(all P<0.05).The drug safety of the study group was higher than that of the con-trol group,but the difference was not statistically significant(P>0.05).Conclusion The combined treatment of lipoic acid and telmisartan in diabetic nephropathy can improve the blood glucose level,renal hemodynamics and renal func-tion of patients with diabetic nephropathy,and the drug is safe.

Diabetic nephropathyLipoic acidTelmisartanBlood glucose levelsHemodynamics

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蒙阴县人民医院老年科,山东 临沂 276200

糖尿病肾病 硫辛酸 替米沙坦 血糖水平 血流动力学

2024

糖尿病新世界
中国病理生理学会

糖尿病新世界

影响因子:0.461
ISSN:1672-4062
年,卷(期):2024.27(9)
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