胰岛素泵注治疗糖尿病患儿的疗效研究
Therapeutic Effect of Insulin Pumping in the Treatment of Diabetic Chil-dren
郑凰凤 1姚冬青 1张幼婷1
作者信息
- 1. 晋江市医院(上海市第六人民医院福建医院),福建 晋江 362200
- 折叠
摘要
目的 分析胰岛素泵注治疗糖尿病患儿的疗效.方法 回顾性选取2022年6月—2024年1月晋江市医院(上海市第六人民医院福建医院)收治的102例糖尿病患儿的临床资料,根据治疗方式的不同分为两组,各51例.对照组治疗方式为注射胰岛素,研究组治疗方式为泵注胰岛素,两组治疗时间均为1个月.对比两组治疗前后血糖水平(空腹血糖、餐后2 h血糖、糖化血红蛋白)、胰岛素水平(空腹胰岛素、胰岛β功能指数、胰岛素抵抗指数)、治疗情况(血糖达标时间及胰岛素日用量)与不良反应(皮肤过敏、感染、疼痛、低血糖)发生情况.结果 治疗后,研究组糖化血红蛋白、空腹血糖、餐后2 h血糖水平较对照组更低,差异有统计学意义(P均<0.05).研究组血糖达标时间及胰岛素日用量均少于对照组,差异有统计学意义(P均<0.05).研究组胰岛素水平优于对照组,差异有统计学意义(P均<0.05).研究组不良反应总发生率低于对照组,差异有统计学意义(P<0.05).结论 胰岛素泵注治疗糖尿病患儿,能够有效降低血糖水平,改善胰岛素水平,且不良反应发生风险较低,有助于患儿早日康复.
Abstract
Objective To analyze the therapeutic effect of insulin pumping in the treatment of diabetic children.Methods Clinical data of 102 diabetic children admitted to Jinjiang Hospital(Shanghai Sixth People's Hospital Fu-jian Hospital)from June 2022 to January 2024 were retrospectively selected and divided into two groups with 51 cases each according to different treatment methods.The treatment method of the control group was insulin injection,and the treatment method of the study group was insulin pump injection.The treatment time of both groups was 1 month.Before and after treatment,blood glucose levels(fasting blood glucose,2-hour postprandial blood glucose,glycated he-moglobin A1c),insulin levels(fasting insulin,islet β function index,insulin resistance index),treatment conditions(time of blood glucose compliance and daily insulin dosage)and incidence of adverse reactions(Skin allergy,infection,pain,hypoglycemia)of the two groups were compared.Results After treatment,the levels of glycoated hemoglobin A1c,fasting blood glucose and 2-hour postprandial blood glucose in the study group were lower than those in the con-trol group,and the differences were statistically significant(all P<0.05).The time of blood glucose compliance and daily insulin dosage in the study group were less than those in the control group,and the differences were statistically significant(both P<0.05).The insulin levels in the study group were better than those in the control group,and the dif-ferences were statistically significant(all P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Insulin pump therapy can effectively reduce blood glucose level and improve insulin level in diabetic children,and the risk of ad-verse reactions is low,which is conducive to the early recovery of children.
关键词
胰岛素泵/糖尿病/胰岛素水平/血糖水平/血糖达标时间Key words
Insulin pump/Diabetes mellitus/Insulin levels/Blood glucose levels/Time of blood glucose compliance引用本文复制引用
出版年
2024
NETL
NSTL
万方数据