Objective To explore the diagnostic value of combined detection of high-sensitivity C-reactive protein,β2 microglobulin and urinary microalbumin in diabetic nephropathy.Methods Clinical data of 40 patients with early dia-betic nephropathy and 40 patients with simple diabetes admitted to Kunming Hospital of Traditional Chinese Medi-cine from January to December 2023 were retrospectively selected.The observation group was diabetic nephropathy,and the control group was simple diabetes.Compared two groups of hypersensitive C-reactive protein,β2 microglobu-lin,blood and urine trace albumin levels.The sensitivity,specificity and area under the curve of hypersensitive C-reactive protein,blood β2 microglobulin and urine trace albumin alone and combined diagnosis of early diabetic ne-phropathy were calculated.Results The levels of high-sensitivity C-reactive protein,blood β2 microglobulin and uri-nary microalbumin in the observation group were higher than those in the control group,and the differences were sta-tistically significant(all P<0.05).The sensitivity,specificity and area under the curve of combined diagnosis of high-sensitivity C-reactive protein,blood β2 microglobulin and urinary microalbumin were higher than those of single diag-nosis.Conclusion The levels of high-sensitivity C-reactive protein,blood β2 microglobulin and urinary microalbu-min in patients with early diabetic nephropathy were increased,and the combined detection of the three had better di-agnostic value.
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